Dr Simon Trent - M.Biochem PhD Bath
Overview
Location: Tower Building, Park Place
Email: TrentS@cardiff.ac.uk
Telephone: +44(0)29 208 75369
+44(0)29 206 87047 (Medic)
Research Summary
I am based in the Schools of Psychology and Medicine at Cardiff University. I am a member of the Behavioural Genetics Group (PSYCH and MEDIC, www.bgg.cf.ac.uk/), the MRC Centre for Neuropsychiatric Genetics and Genomics (PSYCH and MEDIC, www.cf.ac.uk/cngg), the Neuroscience and Mental Health Research Institute and the Institute of Psychological Medicine and Clinical Neurology (MEDIC).
Selected Publications
2013
Trent, S. and Davies, W. (2013). Cognitive, behavioural and psychiatric phenotypes associated with steroid sulfatase deficiency. World Journal of Translational Medicine, 2(1), 1-12. (10.5528/wjtm.v2.i1.1)
2012
Trent, S., Cassano, T., Bedse, G., Ojarikre, O. A., Humby, T. and Davies, W. (2012). Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice. Neuropsychopharmacology, 37(5), 1267-1274. (10.1038/npp.2011.314)
Trent, S., Dean, R., Veit, B., Cassano, T., Bedse, G., Ojarikre, O. A., Humby, T. and Davies, W. (2012). Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder. Psychoneuroendocrinology (10.1016/j.psyneuen.2012.12.002)
2011
Trent, S., Dennehy, A., Richardson, H., Ojarikre, O. A., Burgoyne, P. S., Humby, T. and Davies, W. (2011). Steroid sulfatase-deficient mice exhibit endophenotypes relevant to Attention Deficit Hyperactivity Disorder. Psychoneuroendocrinology, 37(2), 221-229. (10.1016/j.psyneuen.2011.06.006)
Trent, S. and Davies, W. (2011). The influence of sex-linked genetic mechanisms on attention and impulsivity. Biological Psychology, 89(1), 1-13. (10.1016/j.biopsycho.2011.09.011)
2009
Trent, S., Drew, C. J., Mitchell, P. J. and Bailey, S. J. (2009). Chronic treatment with 13-cis-retinoic acid changes aggressive behaviours in the resident-intruder paradigm in rats. European Neuropsychopharmacology, 19(12), 876-886. (10.1016/j.euroneuro.2009.07.003)
Publications
Online Publications
Click on my Researcher ID badge for electronic information about my publications:
Full List of Publications
2013
Trent, S. and Davies, W. (2013). Cognitive, behavioural and psychiatric phenotypes associated with steroid sulfatase deficiency. World Journal of Translational Medicine, 2(1), 1-12. (10.5528/wjtm.v2.i1.1)
2012
Trent, S., Cassano, T., Bedse, G., Ojarikre, O. A., Humby, T. and Davies, W. (2012). Altered serotonergic function may partially account for behavioral endophenotypes in steroid sulfatase-deficient mice. Neuropsychopharmacology, 37(5), 1267-1274. (10.1038/npp.2011.314)
Trent, S., Dean, R., Veit, B., Cassano, T., Bedse, G., Ojarikre, O. A., Humby, T. and Davies, W. (2012). Biological mechanisms associated with increased perseveration and hyperactivity in a genetic mouse model of neurodevelopmental disorder. Psychoneuroendocrinology (10.1016/j.psyneuen.2012.12.002)
2011
Trent, S., Dennehy, A., Richardson, H., Ojarikre, O. A., Burgoyne, P. S., Humby, T. and Davies, W. (2011). Steroid sulfatase-deficient mice exhibit endophenotypes relevant to Attention Deficit Hyperactivity Disorder. Psychoneuroendocrinology, 37(2), 221-229. (10.1016/j.psyneuen.2011.06.006)
Trent, S. and Davies, W. (2011). The influence of sex-linked genetic mechanisms on attention and impulsivity. Biological Psychology, 89(1), 1-13. (10.1016/j.biopsycho.2011.09.011)
2009
Trent, S., Drew, C. J., Mitchell, P. J. and Bailey, S. J. (2009). Chronic treatment with 13-cis-retinoic acid changes aggressive behaviours in the resident-intruder paradigm in rats. European Neuropsychopharmacology, 19(12), 876-886. (10.1016/j.euroneuro.2009.07.003)
2007
O'Reilly, K. C., Trent, S., Bailey, S. J. and Lane, M. A. (2007). 13-cis-retinoic acid alters intracellular serotonin, increases 5-HT1A receptor, and serotonin reuptake transporter levels in vitro. Experimental Biology and Medicine, 232(9), 1195-1203. (10.3181/0703-RM-83)
© Copyright
Some of the documents listed above are available for downloading. These have been provided as a means to ensure timely dissemination of scholarly and technical work on a non-commercial basis. Copyright and all rights therein are maintained by the authors or by other copyright holders, notwithstanding that they have offered their works here electronically. It is understood that all persons copying this information will adhere to the terms and constraints invoked by each author's copyright. These works may not be re-posted without the explicit permission of the copyright holder.
Research
Research Topics and Related Papers
Converging pharmacological and genetic evidence indicates a role for steroid sulfatase in attention. (2009) Davies W, Humby T, Kong W, Otter T, Burgoyne PS, Wilkinson LS. Biol Psychiatry. 66(4):360-7.
X-monosomy effects on visuospatial attention in mice: a candidate gene and implications for Turner syndrome and attention deficit hyperactivity disorder. Davies W, Humby T, Isles AR, Burgoyne PS, Wilkinson LS. Biol Psychiatry. 2007 Jun 15;61(12):1351-60
Genomic imprinting effects on brain development and function. (2007) Wilkinson LS, Davies W, Isles AR. Nat Rev Neurosci. 8(11):832-43.
Funding
My work is funded by an MRC New Investigator Award to Dr William Davies.
Research Collaborators
Dr Trevor Humby (School of Psychology, Cardiff University)
Professor Lawrence Wilkinson (Schools of Psychology and Medicine, Cardiff University)
Dr Paul Burgoyne (MRC National Institute for Medical Research, London, UK)
Dr Jonathan Fry (University College London, UK)
Biography
Undergraduate Education
M.Biochem (2:1 Class) Hon. (University of Bath)
Postgraduate Education
Ph.D. (Neuropharmacology) (University of Bath)