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Ms Jennifer Ware

Overview

person name Research Group: Cognitive Neuroscience Supervisor(s): Andrew Lawrence
Marianne van den Bree (Psych Med)

Location: Heath Park Campus
Email: WareJJ@cardiff.ac.uk
Telephone: +44(0)29 2068 7910

Research Summary

The primary aim of my PhD is to elucidate the mechanisms by which certain candidate genes (namely dopamine pathway genes and the nicotinic receptor gene cluster CHRNA5-A3-B4) influence behavioural, cognitive and affective aspects of smoking. To address this question I am utilising three different approaches: 1. Meta-analysis; 2. Genetic epidemiology; and 3. Neuroimaging. Furthering our understanding of the genetic contribution of smoking-related behaviours may ultimately enable us to improve and personalise smoking cessation treatments.

Teaching Summary

Lecturing experience: Psychology UG (level 2), Introduction to Psychopharmacology.
One-to-one undergraduate tutoring.

Selected Publications (2008 onwards)

Publications

Full List of Publications

Forthcoming

Diukova, A., Ware, J. J., Smith, J. E., Evans, J. C., Murphy, K., Rogers, P. J. & Wise, R. G. (in press). Separating neural and vascular effects of caffeine using simultaneous EEG-FRI: differential effects of caffeine on cognitive and sensorimotor brain responses. NeuroImage.

Conferences and Seminars

Ware, J. J., van den Bree, M., & Munafò, M. (2012). Exploring the relationship between genes and smoking behaviour. Poster presentation at Wellcome Trust postgraduate conference, London.

Ware, J.J. (2011). Association of dopamine pathway genotypes with smoking-related cue induced activation. Oral presentation at UKCTCS postgraduate conference, Bath.

Ware, J.J. & David, S. P. (2011). Exploring the relationship between dopamine pathway genotypes and smoking-related cue induced activation: an fMRI study. Oral presentation at SRI International, Menlo Park, California.

Ware, J. J., Heron, J., Munafò, M., & van den Bree, M. (2011). The impact of CHRNA3 and BDNF variants on the association between parental monitoring and smoking initiation. Poster presentation at the Society for Research on Nicotine and Tobacco Annual Meeting, Toronto.

Ware, J. J., van den Bree, M., & Munafò, M. (2010). Association of the CHRNA5-A3-B4 gene cluster with heaviness of smoking. Poster presentation at SfN and NIDA satellite convention ‘Frontiers in Addiction Research’, San Diego.

Ware, J. J., van den Bree, M., & Munafò, M. (2010). Association of the CHRNA5-A3-B4 gene cluster with heaviness of smoking. Poster presentation at the British Association for Psychopharmacology summer meeting, Harrogate.

Ware, J. J., van den Bree, M., Lawrence, A. & Munafò, M. (2010). Exploring the relationship between COMT and CHRNA5/A3/B4 and smoking related phenotypes: A genetic and neuroimaging study. Invited speaker at UKCRC Public Health Research Centres of Excellence first joint meeting. Queens College, Cambridge.

Ware, J.J., van den Bree, M., Lawrence, A. & Munafò, M. (2010). Exploring the relationship between COMT and CHRNA5/A3/B4 and smoking related phenotypes: A genetic and neuroimaging study. Invited speaker and poster presentation at UKCTCS Postgraduate and Fellow Conference, Nottingham.

Ware, J. J. & van den Bree, M. (2010) Childhood abuse and adult psychopathology: A large, randomised study of homeless people in the UK. Invited speaker at European Collaborative Research Day, Heath Hospital, Cardiff.

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Media

Media Activities

2010
Brain Awareness Week
Confocal microscopy tour and presentation (general public).
Brain awareness workshop with 100 10 year olds from local schools.

2011
STEM Careers event – St Cyres School

Research

Funding

Wellcome Trust studentship

Research Group

Section of Forensic Psychiatry and Substance Misuse, Institute of Psychological Medicine and Clinical Neurosciences, Cardiff University.

Tobacco and Alcohol Research Group, School of Experimental Psychology, University of Bristol.

Research Collaborators

Dr Marianne van den Bree (Cardiff Univeristy)

Prof Andrew Lawrence (Cardiff Unviersity)

Prof Marcus Munafò (Experimental Psychology Dept., University of Bristol, UK)

Prof Sean David (School of Medicine, Stanford University, California)

Biography

Undergraduate Education

2003-2006: Psychology BSc, 2:1, Cardiff University

Postgraduate Education

2008 - present: Wellcome Trust 4-year PhD in Integrative Neuroscience, Cardiff University

Awards and Prizes

SRNT Young Investigator Travel Scholarship (to attend NIDA satellite convention ‘Frontiers in Addiction Research’ at Society for Neuroscience 2011 annual meeting, San Diego).

British Association for Psychopharmacology Travel Award (to attend BAP 2010 annual summer meeting, Harrogate).

Stuart Dimond Memorial Prize for best undergraduate research project in 2005/06, awarded by Cardiff University.

Professional Memberships

Society for Research on Nicotine and Tobacco (SRNT)
UK Centre for Tobacco Control Studies (UKCTCS)
Society for Neuroscience (SfN)
British Association for Psychopharmacology (BAP)

Reviewer Contributions

PLoS ONE
Journal of Adolescent Health
Pharmacogenetics and Genomics
Addiction Biology
Nicotine and Tobacco Research
Addictive Behaviors
Drug and Alcohol Dependence
American Journal of Psychiatry
Abstract reviewer for SRNT 2012 annual meeting