Alzheimer's Disease is the leading cause of dementia and is charaterised by chronic neurodegeneration as well as the accumulations of β-amyloid "plaques" and tau "tangles". The aggregation of β-amyloid peptides was first proposed as the cause of the disease in 1991. However, we still have no disease modifying therapies.
My research aims to uncover a physiological role for the β-amyloid in normal cognition. We will use an antibody to inhibit its production, before analysing any effect on learning and memory. We will also utilise a novel murine model of the disease which more accurately represents the human condition.
Full list of publications
Dr Emma Kidd (Pharmacy)
Dr Rhian Thomas (Pharmacy)
Master of Natural Sciences (Biomedical Science & Chemical Biology) 2011-2015: First Class Honours, University of Southampton
April 2016 - Present: Wellcome Trust 4 Year PhD in Integrative Neuroscience
June - August 2012 Wellcome Trust Vacation Scholarship, University of Southampton, Professor Peter Roach