Professor Derek K Jones - BSc Nottingham MSc Leeds PhD Leicester Dip. IPSM

Professor

Research group:
Neuroscience
Email:
JonesD27@cardiff.ac.uk
Telephone:
+44(0)29 2087 9412
Location:
CUBRIC, Maindy Road

Research summary

The main aim of CUBRIC is to develop imaging methodology to improve characterization of brain structure and function in health and disease.  My research focuses on maximizing the amount of quantitative information that can be extracted about brain structure non-invasively using magnetic resonance imaging techniques.  If the grey matter acts as the ‘service stations’ – then the white matter acts as the ‘motorways’ and hence forms an integral and fundamental part of brain networks. My research has been primarily focussed on development of methods for diffusion magnetic resonance imaging and its application to both healthy and diseased states, but we are extending the range of imaging methods to include multi-component relaxometry and quantitative magnetization transfer imaging, with the aim of providing a more complete multi-spectral characterization of white matter.  We are now combining these metrics with electrophysiological data derived from MEG.

Teaching summary

In the University, I teach formally on lecture course PS3209 – ‘Structural and Functional Neuroimaging’, which introduces the range of techniques that are used for mapping the structure and function of the human brain.  My part of the course focuses on mapping brain structure, and includes methods for analysis of standard structural MRI data, as well as of diffusion MRI data. 

I also teach at the postgraduate level on the use of diffusion MRI.  Formal courses are held throughout the year and cover both theoretical aspects of diffusion MRI as well as practical ‘hands on’ sessions with software developed in CUBRIC.

Finally, I am a regular lecturer at international brain imaging conferences (notably the International Society for Magnetic Resonance In Medicine, and the ESMRMB Lectures on Diffusion).

Selected publications (2008 onwards)

2016

Bracht, T. K., Jones, D., Bells, S., Walther, S., Drakesmith, M. and Linden, D. (2016). Myelination of the right parahippocampal cingulum is associated with physical activity in young healthy adultsBrain Structure and Function (10.1007/s00429-016-1183-3) pdf

Caeyenberghs, K., Metzler-Baddeley, C., Foley, S. and Jones, D. (2016). Dynamics of the human structural connectome underlying working memory trainingJournal of Neuroscience, 36(14), 4056-4066. (10.1523/JNEUROSCI.1973-15.2016)

De Santis, S., Jones, D. K. and Roebroeck, A. (2016). Including diffusion time dependence in the extra-axonal space improves in vivo estimates of axonal diameter and density in human white matterNeuroImage, 130, 91-103. (10.1016/j.neuroimage.2016.01.047) pdf

Dimitriadis, S., Linden, D. E. J., Singh, K. D. and Jones, D. K. (2016). A prolonged maturational time course in brain development for cortical processing of temporal modulationsClinical Neurophysiology, 127(2), 994-998. (10.1016/j.clinph.2015.09.001)

Keedwell, P. A., Doidge, A. N., Meyer, M., Lawrence, N., Lawrence, A. D. and Jones, D. K. (2016). Subgenual cingulum microstructure supports control of emotional conflictCerebral Cortex, 26(6), 2850-2862. (10.1093/cercor/bhw030) pdf

Metzler-Baddeley, C., Caeyenberghs, K., Foley, S. and Jones, D. K. (2016). Longitudinal data on cortical thickness before and after working memory trainingData in Brief, 7, 1143-1147. (10.1016/j.dib.2016.03.090) pdf

Metzler-Baddeley, C., Caeyenberghs, K., Foley, S. and Jones, D. K. (2016). Task complexity and location specific changes of cortical thickness in executive and salience networks after working memory trainingNeuroImage, 130, 48-62. (10.1016/j.neuroimage.2016.01.007) pdf

Rees, D. A., Udiawar, M., Berlot, R., Jones, D. K. and O'Sullivan, M. J. (2016). White matter microstructure and cognitive function in young women with polycystic ovary syndromeJournal of Clinical Endocrinology & Metabolism, 101(1), 314-323. (10.1210/jc.2015-2318) pdf

2015

Bracht, T., Doidge, A. N., Keedwell, P. A. and Jones, D. K. (2015). Hedonic tone is associated with left supero-lateral medial forebrain bundle microstructurePsychological Medicine, 45(4), 865-874. (10.1017/S0033291714001949) pdf

Bracht, T., Jones, D. K., Müller, T. J., Wiest, R. and Walther, S. (2015). Limbic white matter microstructure plasticity reflects recovery from depressionJournal of affective disorders, 170, 143-149. (10.1016/j.jad.2014.08.031)

Bracht, T., Jones, D. K., Müller, T. J., Wiest, R. and Walther, S. (2015). Limbic white matter microstructure plasticity reflects recovery from depressionJournal of Affective Disorders, 170, 143-149. (10.1016/j.jad.2014.08.031)

Caseras, X., Murphy, K., Lawrence, N. S., Fuentes-Claramonte, P., Watts, J., Jones, D. K. and Phillips, M. L. (2015). Emotion regulation deficits in euthymic bipolar I versus bipolar II disorder: a functional and diffusion-tensor imaging studyBipolar Disorders, 17(5), 461-470. (10.1111/bdi.12292) pdf

Cooper, M., Thapar, A. and Jones, D. K. (2015). ADHD severity is associated with white matter microstructure in the subgenual cingulumNeuroImage: Clinical, 7, 653-660. (10.1016/j.nicl.2015.02.012) pdf

Cooper, M., Thapar, A. and Jones, D. K. (2015). ADHD severity is associated with white matter microstructure in the subgenual cingulumNeuroImage: Clinical, 7, 653-660. (10.1016/j.nicl.2015.02.012)

De Santis, S., Barazany, D., Jones, D. K. and Assaf, Y. (2015). Resolving relaxometry and diffusion properties within the same voxel in the presence of crossing fibres by combining inversion recovery and diffusion-weighted acquisitionsMagnetic Resonance in Medicine, 75(1), 372-380. (10.1002/mrm.25644) pdf

Drakesmith, M., Caeyenberghs, K., Dutt, A., Zammit, S., Evans, C. J., Reichenberg, A., Lewis, G., David, A. S. and Jones, D. K. (2015). Schizophrenia-like topological changes in the structural connectome of individuals with subclinical psychotic experiencesHuman Brain Mapping, 36(7), 2629-2643. (10.1002/hbm.22796) pdf

Dutt, A., Tseng, H., Fonville, L., Drakesmith, M., Su, L., Evans, J., Zammit, S., Jones, D., Lewis, G. and David, A. S. (2015). Exploring neural dysfunction in 'clinical high risk' for psychosis: A quantitative review of fMRI studiesJournal of Psychiatric Research, 61, 122-134. (10.1016/j.jpsychires.2014.08.018)

Hodgetts, C. J., Postans, M., Shine, J. P., Jones, D. K., Lawrence, A. D. and Graham, K. S. (2015). Dissociable roles of the inferior longitudinal fasciculus and fornix in face and place perceptioneLife, 4 (10.7554/eLife.07902) pdf

Ray, N., Metzler-Baddeley, C., Khondoker, M., Grothe, M., Teipel, S., Wright, P., Heinsen, H., Jones, D. K., Aggleton, J. P. and O'Sullivan, M. J. (2015). Cholinergic basal forebrain structure influences the reconfiguration of white matter connections to support residual memory in Mild Cognitive ImpairmentJournal of Neuroscience, 35(2), 739-747. (10.1523/JNEUROSCI.3617-14.2015) pdf

Steventon, J., Harrison, D. J., Trueman, R. C., Rosser, A. E., Jones, D. K. and Brooks, S. P. (2015). In Vivo MRI evidence that neuropathology is attenuated by cognitive enrichment in the Yac128 Huntington's Disease mouse modelJournal of Huntington's Disease, 4(2), 149-160. (10.3233/JHD-150147)

Steventon, J., Trueman, R. C., Rosser, A. E. and Jones, D. K. (2015). Robust MR-based approaches to quantifying white matter structure and structure/function alterations in Huntington's diseaseJournal of Neuroscience Methods, 265, 2-12. (10.1016/j.jneumeth.2015.08.027) pdf

2014

Berlot, R., Metzler-Baddeley, C., Jones, D. K. and O'Sullivan, M. (2014). CSF contamination contributes to apparent microstructural alterations in mild cognitive impairmentNeuroImage, 92, 27-35. (10.1016/j.neuroimage.2014.01.031)

Caeyenberghs, K., Powell, H., Thomas, R. H., Brindley, L., Church, C., Evans, J., Muthukumaraswamy, S., Jones, D. and Hamandi, K. (2014). Hyperconnectivity in juvenile myoclonic epilepsy: A network analysisNeuroImage: Clinical, 7, 98-104. (10.1016/j.nicl.2014.11.018)

Chantiluke, K., Christakou, A., Murphy, C. M., Giampietro, V., Daly, E. M., Ecker, C., Brammer, M., Murphy, D. G., Rubia, K. and Jones, D. (2014). Disorder-specific functional abnormalities during temporal discounting in youth with Attention Deficit Hyperactivity Disorder (ADHD), Autism and comorbid ADHD and AutismPsychiatry Research: Neuroimaging, 223(2), 113. (10.1016/j.pscychresns.2014.04.006)

Cooper, M., Thapar, A. and Jones, D. (2014). Erratum to: White matter microstructure predicts autistic traits in Attention-Deficit/Hyperactivity DisorderJournal of Autism and Developmental Disorders, 44(11), 2755. (10.1007/s10803-014-2162-2)

Cooper, M., Thapar, A. and Jones, D. K. (2014). White matter microstructure predicts autistic traits in attention-deficit/hyperactivity disorderJournal of Autism and Developmental Disorders, 44(11), 2742-2754. (10.1007/s10803-014-2131-9) pdf

De Santis, S., Assaf, Y., Evans, C. J. and Jones, D. K. (2014). Improved precision in CHARMED assessment of white matter through sampling scheme optimization and model parsimony testingMagnetic Resonance in Medicine, 71(2), 661-671. (10.1002/mrm.24717)

De Santis, S., Drakesmith, M., Bells, S., Assaf, Y. and Jones, D. K. (2014). Why diffusion tensor MRI does well only some of the time: Variance and covariance of white matter tissue microstructure attributes in the living human brainNeuroImage, 89, 35-44. (10.1016/j.neuroimage.2013.12.003) pdf

Metzler-Baddeley, C., Cantera, J., Coulthard, E., Rosser, A. E., Jones, D. K. and Baddeley, R. J. (2014). Improved executive function and callosal white matter microstructure after rhythmn exercise in Huntington's diseaseJournal of Huntington's Disease, 3(3), 273-283. (10.3233/JHD-140113)

Postans, M., Hodgetts, C. J., Mundy, M. E., Jones, D. K., Lawrence, A. D. and Graham, K. S. (2014). Individual variation in fornix microstructure and macrostructure is related to visual discrimination accuracy for scenes but not facesJournal of Neuroscience, 34(36), 12121-12126. (10.1523/JNEUROSCI.0026-14.2014) pdf

Powell, R., Caeyenberghs, K., Thomas, R. H., Jones, J. D. K. and Hamandi, K. (2014). Hyperconnectivity in JME-a network analysisJournal of Neurology, Neurosurgery & Psychiatry, 85(10) (10.1136/jnnp-2014-309236.5)

2013

Assaf, Y., Alexander, D. C., Jones, D. K., Bizzi, A., Behrens, T. E. J., Clark, C. A., Cohen, Y., Dyrby, T. B., Huppi, P. S., Knoesche, T. R., LeBihan, D., Parker, G. J. M. and Poupon, C. (2013). The CONNECT project: Combining macro- and micro-structureNeuroImage, 80, 273-282. (10.1016/j.neuroimage.2013.05.055)

De Santis, S., Evans, C. J. and Jones, D. K. (2013). RAPID: A routine assurance pipeline for imaging of diffusionMagnetic Resonance in Medicine, 70(2), 490-496. (10.1002/mrm.24465)

De Santis, S., Assaf, Y., Bells, S., Deoni, S. C. and Jones, D. K. (2013). The CONNECT brain atlas of white matter microstructure [Conference Material]Proceedings of the International Society for Magnetic Resonance Imaging, 21, 843-843.

Jeurissen, B., Leemans, A., Tournier, J., Jones, D. K. and Sijbers, J. (2013). Investigating the prevalence of complex fiber configurations in white matter tissue with diffusion magnetic resonance imagingHuman Brain Mapping, 34(11), 2747-2766. (10.1002/hbm.22099)

Jones, D. K. and Linden, D. E. J. (2013). Abstracts of Presentations at the International Conference on Basic and Clinical Multimodal Imaging (BaCI), a Joint Conference of the International Society for Neuroimaging in Psychiatry (ISNIP), the International Society for Functional Source Imaging (ISFSI), the International Society for Bioelectromagnetism (ISBEM), the International Society for Brain Electromagnetic Topography (ISBET), and the EEG and Clinical Neuroscience Society (ECNS), in Geneva, Switzerland, September 5-8, 2013Clinical EEG and Neuroscience, 44(4), E1. (10.1177/1550059413507209)

Jones, D. K., Christiansen, K. Y., Chapman, R. J. and Aggleton, J. (2013). Distinct subdivisions of the cingulum bundle revealed by diffusion MRI fibre tracking: Implications for europsychological investigations.Neuropsychologia, 51(1), 67-78. (10.1016/j.neuropsychologia.2012.11.018) pdf

Metzler-Baddeley, C., Baddeley, R. J., Jones, D. K., Aggleton, J. P. and O'Sullivan, M. (2013). Individual differences in fornix microstructure and body mass indexPLoS ONE, 8(3) (10.1371/journal.pone.0059849) pdf

Parker, G., Marshall, A. D., Rosin, P. L., Drage, N., Richmond, S. and Jones, D. K. (2013). A pitfall in the reconstruction of fibre ODFs using spherical deconvolution of diffusion MRI dataNeuroImage, 65, 433-448. (10.1016/j.neuroimage.2012.10.022)

2012

Anderson, E. J., Jones, D. K., O'Gorman, R. L., Leemans, A., Catani, M. and Husain, M. (2012). Cortical network for gaze control in humans revealed using multimodal MRICerebral Cortex, 22(4), 765-775. (10.1093/cercor/bhr110) pdf

Ben-Amitay, S., Jones, D. K. and Assaf, Y. (2012). Motion correction and registration of high b-value diffusion weighted imagesMagnetic Resonance in Medicine, 67(6), 1694-1702. (10.1002/mrm.23186)

De Santis, S., Assaf, Y. and Jones, D. K. (2012). Using the biophysical CHARMED model to elucidate the underpinnings of contrast in diffusional kurtosis analysis of diffusion-weighted MRIMagnetic Resonance Materials in Physics, Biology and Medicine, 25(4), 267-276. (10.1007/s10334-011-0292-5)

Ecker, C. et al. (2012). Brain Anatomy and Its Relationship to Behavior in Adults With Autism Spectrum Disorder: A Multicenter Magnetic Resonance Imaging StudyArchives of General Psychiatry, 69(2), 195-209. (10.1001/archgenpsychiatry.2011.1251)

Keedwell, P. A., Chapman, R. J., Christiansen, K. Y., Richardson, H., Evans, C. J. and Jones, D. K. (2012). Cingulum white matter in young women at risk of depression: The effect of family history and anhedoniaBiological Psychiatry, 72(4), 296-302. (10.1016/j.biopsych.2012.01.022)

Metzler-Baddeley, C., Jones, D. K., Steventon, J., Westacott, L., Aggleton, J. P. and O'Sullivan, M. (2012). Cingulum microstructure predicts cognitive control in older age and mild cognitive impairmentJournal of Neuroscience, 32(49), 17612-17619. (10.1523/JNEUROSCI.3299-12.2012) pdf

Metzler-Baddeley, C., O'Sullivan, M., Bells, S., Pasternak, O. and Jones, D. K. (2012). How and how not to correct for CSF-contamination in diffusion MRINeuroimage, 59(2), 1394-1403. (10.1016/j.neuroimage.2011.08.043)

Metzler-Baddeley, C., Hunt, S., Jones, D. K., Leemans, A., Aggleton, J. P. and O'Sullivan, M. (2012). Temporal association tracts and the breakdown of episodic memory in mild cognitive impairmentNeurology, 79(23), 2233-2240. (10.1212/WNL.0b013e31827689e8)

Richmond, S. et al. (2012). Detailing patient specific modeling to aid clinical decision-makingLecture Notes in Computational Vision and Biomechanics, 5, 105-131. (10.1007/978-94-007-4552-0_5)

Sundram, F. et al. (2012). White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorderCortex, 48(2), 216-229. (10.1016/j.cortex.2011.06.005)

Vos, S. B., Jones, D. K., Jeurissen, B., Viergever, M. A. and Leemans, A. (2012). The influence of complex white matter architecture on the mean diffusivity in diffusion tensor MRI of the human brainNeuroImage, 59(3), 2208-2216. (10.1016/j.neuroimage.2011.09.086)

2011

(2011). Diffusion MRI: theory, methods and applications. Oxford: Oxford University Press.

Blain, C. R. V., Brunton, S., Williams, V. C., Leemans, A., Turner, M. R., Andersen, P. M., Catani, M., Stanton, B. R., Ganesalingham, J., Jones, D. K., Williams, S. C. R., Leigh, P. N. and Simmons, A. (2011). Differential corticospinal tract degeneration in homozygous 'D90A' SOD-1 ALS and sporadic ALSJournal of Neurology, Neurosurgery & Psychiatry, 82(8), 843-849. (10.1136/jnnp.2010.236018)

Edden, R. A. E. and Jones, D. K. (2011). Spatial and orientational heterogeneity in the statistical sensitivity of skeleton-based analyses of diffusion tensor MR imaging dataJournal of Neuroscience Methods, 201(1), 213-219. (10.1016/j.jneumeth.2011.07.025)

Jeurissen, B., Leemans, A., Jones, D. K., Tournier, J. and Sijbers, J. (2011). Probabilistic fiber tracking using the residual bootstrap with constrained spherical deconvolutionHuman Brain Mapping, 32(3), 461-479. (10.1002/hbm.21032)

Jones, D. K. and Leemans, A. (2011). Diffusion tensor imaging. In: Modo, M. and Bulte, J. eds. Magnetic Resonance Neuroimaging: Methods and Protocols, Vol 711. Springer, pp. 127-144. (10.1007/978-1-61737-992-5_6)

Lai, M. et al. (2011). A Behavioral Comparison of Male and Female Adults with High Functioning Autism Spectrum ConditionsPLoS ONE, 6(6) (10.1371/journal.pone.0020835) pdf

Lombardo, M. V., Chakrabarti, B., Bullmore, E. T., Baron-Cohen, S., Bailey, A. J., Bolton, P. F., Carrington, S. J., Daly, E. M., Deoni, S. C., Ecker, C., Happé, F., Henty, J., Jezzard, P., Johnston, P., Jones, D. K., Lai, M. C., Madden, A., Mullins, D., Murphy, C. and Murphy, D. G. M. (2011). Specialization of right temporo-parietal junction for mentalizing and its relation to social impairments in autismNeuroImage, 56(3), 1832-1838. (10.1016/j.neuroimage.2011.02.067)

Metzler-Baddeley, C., Jones, D. K., Belaroussi, B., Aggleton, J. P. and O'Sullivan, M. (2011). Frontotemporal connections in episodic memory and aging: A diffusion MRI tractography studyThe Journal of Neuroscience, 31(37), 13236-13245. (10.1523/JNEUROSCI.2317-11.2011) pdf

Metzler-Baddeley, C., Jones, D. K., Aggleton, J. P. and O'Sullivan, M. (2011). The fornix in ageing and memory decline: a diffusion MRI tractography study [Abstract]Journal of Neurology, 258(S1), 18-18. (10.1007/s00415-011-6026-9)

Vos, S. B., Jones, D. K., Viergever, M. A. and Leemans, A. (2011). Partial volume effect as a hidden covariate in DTI analysesNeuroImage, 55(4), 1566-1576. (10.1016/j.neuroimage.2011.01.048)

2010

Bloemen, O. J. N., Deeley, Q., Sundram, F., Daly, E. M., Barker, G. J., Jones, D. K., van Amelsvoort, T. A. M. J., Schmitz, N., Robertson, D., Murphy, K. C. and Murphy, D. G. M. (2010). White matter integrity in Asperger syndrome: a preliminary diffusion tensor magnetic resonance imaging study in adultsAutism Research, 3(5), 203-213. (10.1002/aur.146)

Ecker, C. et al. (2010). Investigating the predictive value of whole-brain structural MR scans in autism: A pattern classification approachNeuroImage, 49(1), 44-56. (10.1016/j.neuroimage.2009.08.024)

Jones, D. K. (2010). Challenges and limitations of quantifying brain connectivity in vivo with diffusion MRIImaging in Medicine, 2(3), 341-355. (10.2217/iim.10.21)

Jones, D. K. (2010). Precision and Accuracy in Diffusion Tensor Magnetic Resonance ImagingTopics in Magnetic Resonance Imaging, 21(2), 87-99. (10.1097/RMR.0b013e31821e56ac)

Jones, D. K. and Cercignani, M. (2010). Twenty-five pitfalls in the analysis of diffusion MRI dataNMR in Biomedicine, 23(7), 803-820. (10.1002/nbm.1543)

Lombardo, M. et al. (2010). Atypical neural self-representation in autismBrain, 133(2), 611-624. (10.1093/brain/awp306)

Lombardo, M. et al. (2010). Shared Neural Circuits for Mentalizing about the Self and OthersJournal of Cognitive Neuroscience, 22(7), 1623-1635. (10.1162/jocn.2009.21287) pdf

Muthukumaraswamy, S. D., Singh, K. D., Swettenham, J. B. and Jones, D. K. (2010). Visual gamma oscillations and evoked responses: Variability, repeatability and structural MRI correlatesNeuroImage, 49(4), 3349-3357. (10.1016/j.neuroimage.2009.11.045)

Sundram, F., Campbell, L. E., Azuma, R., Daly, E., Bloemen, O. J. N., Barker, G. J., Chitnis, X., Jones, D. K., Amelsvoort, T., Murphy, K. C. and Murphy, D. G. M. (2010). White matter microstructure in 22q11 deletion syndrome: a pilot diffusion tensor imaging and voxel-based morphometry study of children and adolescentsJournal of Neurodevelopmental Disorders, 2(2), 77-92. (10.1007/s11689-010-9043-6)

2009

Jones, D. K. (2009). Fundamentals of diffusion MR imaging. In: Gillard, J., Waldman, A. and Barker, P. eds. Clinical MR Neuroimaging: Physiological and Functional Techniques. 2nd ed.. Cambridge: Cambridge University Press, pp. 44-67.

Jones, D. K. (2009). Gaussian modeling of the diffusion signal. In: Johansen-Berg, H. and Behrens, T. eds. Diffusion MRI: From Quantitative Measurement to In vivo Neuroanatomy. Amsterdam: Elsevier, pp. 37-64. (10.1016/B978-0-12-374709-9.00003-1)

Kanaan, R. A. A., Borgwardt, S., McGuire, P. K., Craig, M. C., Murphy, D. G. M., Picchioni, M., Shergill, S. S., Jones, D. K. and Catani, M. (2009). Microstructural Organization of Cerebellar Tracts in SchizophreniaBiological Psychiatry, 66(11), 1067-1069. (10.1016/j.biopsych.2009.07.028)

Kontis, D., Catani, M., Cuddy, M., Walshe, M., Nosarti, C., Jones, D. K., Wyatt, J., Rifkin, L., Murray, R. and Allin, M. (2009). Diffusion tensor MRI of the corpus callosum and cognitive function in adults born pretermNeuroReport, 20(4), 424-428. (10.1097/WNR.0b013e328325a8f9)

Leemans, A. and Jones, D. K. (2009). The B-matrix must be rotated when correcting for subject motion in DTI dataMagnetic Resonance in Medicine, 61(6), 1336-1349. (10.1002/mrm.21890)

Muthukumaraswamy, S. D., Edden, R. A. E., Jones, D. K., Swettenham, J. B. and Singh, K. D. (2009). Resting GABA concentration predicts peak gamma frequency and fMRI amplitude in response to visual stimulation in humansProceedings of the National Academy of Sciences of the United States of America, 106(20), 8356-8361. (10.1073/pnas.0900728106)

2008

Catani, M., Jones, D. K., Daly, E., Embiricos, N., Deeley, Q., Pugliese, L., Curran, S., Robertson, D. and Murphy, D. G. M. (2008). Altered cerebellar feedback projections in Asperger syndromeNeuroImage, 41(4), 1184-1191. (10.1016/j.neuroimage.2008.03.041)

Deoni, S. C. L., Rutt, B. K., Arun, T., Pierpaoli, C. and Jones, D. K. (2008). Gleaning Multicomponent T-1 and T-2 Information From Steady-State Imaging DataMagnetic Resonance in Medicine, 60(6), 1372-1387. (10.1002/mrm.21704)

Deoni, S. C. L., Williams, S. C., Jezzard, P., Suckling, J., Murphy, D. G. M. and Jones, D. K. (2008). Standardized Structural Magnetic Resonance Imaging in Multicenter Studies using Quantitative T1 and T2 Imaging at 1.5TNeuroImage, 40(2), 662-671. (10.1016/j.neuroimage.2007.11.052)

Jones, D. K. (2008). Studying connections in the living human brain with diffusion MRICortex, 44(8), 936-952. (10.1016/j.cortex.2008.05.002)

Jones, D. K. (2008). Tractography gone wild: Probabilistic fibre tracking using the wild bootstrap with diffusion tensor MRIIEEE Transactions on Medical Imaging, 27(9), 1268-1274. (10.1109/TMI.2008.922191)

Online publications

Full list of publications

2016

Bracht, T. K., Jones, D., Bells, S., Walther, S., Drakesmith, M. and Linden, D. (2016). Myelination of the right parahippocampal cingulum is associated with physical activity in young healthy adultsBrain Structure and Function (10.1007/s00429-016-1183-3) pdf

Caeyenberghs, K., Metzler-Baddeley, C., Foley, S. and Jones, D. (2016). Dynamics of the human structural connectome underlying working memory trainingJournal of Neuroscience, 36(14), 4056-4066. (10.1523/JNEUROSCI.1973-15.2016)

De Santis, S., Jones, D. K. and Roebroeck, A. (2016). Including diffusion time dependence in the extra-axonal space improves in vivo estimates of axonal diameter and density in human white matterNeuroImage, 130, 91-103. (10.1016/j.neuroimage.2016.01.047) pdf

Dimitriadis, S., Linden, D. E. J., Singh, K. D. and Jones, D. K. (2016). A prolonged maturational time course in brain development for cortical processing of temporal modulationsClinical Neurophysiology, 127(2), 994-998. (10.1016/j.clinph.2015.09.001)

Keedwell, P. A., Doidge, A. N., Meyer, M., Lawrence, N., Lawrence, A. D. and Jones, D. K. (2016). Subgenual cingulum microstructure supports control of emotional conflictCerebral Cortex, 26(6), 2850-2862. (10.1093/cercor/bhw030) pdf

Metzler-Baddeley, C., Caeyenberghs, K., Foley, S. and Jones, D. K. (2016). Longitudinal data on cortical thickness before and after working memory trainingData in Brief, 7, 1143-1147. (10.1016/j.dib.2016.03.090) pdf

Metzler-Baddeley, C., Caeyenberghs, K., Foley, S. and Jones, D. K. (2016). Task complexity and location specific changes of cortical thickness in executive and salience networks after working memory trainingNeuroImage, 130, 48-62. (10.1016/j.neuroimage.2016.01.007) pdf

Rees, D. A., Udiawar, M., Berlot, R., Jones, D. K. and O'Sullivan, M. J. (2016). White matter microstructure and cognitive function in young women with polycystic ovary syndromeJournal of Clinical Endocrinology & Metabolism, 101(1), 314-323. (10.1210/jc.2015-2318) pdf

2015

Bracht, T., Doidge, A. N., Keedwell, P. A. and Jones, D. K. (2015). Hedonic tone is associated with left supero-lateral medial forebrain bundle microstructurePsychological Medicine, 45(4), 865-874. (10.1017/S0033291714001949) pdf

Bracht, T., Jones, D. K., Müller, T. J., Wiest, R. and Walther, S. (2015). Limbic white matter microstructure plasticity reflects recovery from depressionJournal of affective disorders, 170, 143-149. (10.1016/j.jad.2014.08.031)

Bracht, T., Jones, D. K., Müller, T. J., Wiest, R. and Walther, S. (2015). Limbic white matter microstructure plasticity reflects recovery from depressionJournal of Affective Disorders, 170, 143-149. (10.1016/j.jad.2014.08.031)

Caseras, X., Murphy, K., Lawrence, N. S., Fuentes-Claramonte, P., Watts, J., Jones, D. K. and Phillips, M. L. (2015). Emotion regulation deficits in euthymic bipolar I versus bipolar II disorder: a functional and diffusion-tensor imaging studyBipolar Disorders, 17(5), 461-470. (10.1111/bdi.12292) pdf

Cooper, M., Thapar, A. and Jones, D. K. (2015). ADHD severity is associated with white matter microstructure in the subgenual cingulumNeuroImage: Clinical, 7, 653-660. (10.1016/j.nicl.2015.02.012) pdf

Cooper, M., Thapar, A. and Jones, D. K. (2015). ADHD severity is associated with white matter microstructure in the subgenual cingulumNeuroImage: Clinical, 7, 653-660. (10.1016/j.nicl.2015.02.012)

De Santis, S., Barazany, D., Jones, D. K. and Assaf, Y. (2015). Resolving relaxometry and diffusion properties within the same voxel in the presence of crossing fibres by combining inversion recovery and diffusion-weighted acquisitionsMagnetic Resonance in Medicine, 75(1), 372-380. (10.1002/mrm.25644) pdf

Drakesmith, M., Caeyenberghs, K., Dutt, A., Zammit, S., Evans, C. J., Reichenberg, A., Lewis, G., David, A. S. and Jones, D. K. (2015). Schizophrenia-like topological changes in the structural connectome of individuals with subclinical psychotic experiencesHuman Brain Mapping, 36(7), 2629-2643. (10.1002/hbm.22796) pdf

Dutt, A., Tseng, H., Fonville, L., Drakesmith, M., Su, L., Evans, J., Zammit, S., Jones, D., Lewis, G. and David, A. S. (2015). Exploring neural dysfunction in 'clinical high risk' for psychosis: A quantitative review of fMRI studiesJournal of Psychiatric Research, 61, 122-134. (10.1016/j.jpsychires.2014.08.018)

Hodgetts, C. J., Postans, M., Shine, J. P., Jones, D. K., Lawrence, A. D. and Graham, K. S. (2015). Dissociable roles of the inferior longitudinal fasciculus and fornix in face and place perceptioneLife, 4 (10.7554/eLife.07902) pdf

Ray, N., Metzler-Baddeley, C., Khondoker, M., Grothe, M., Teipel, S., Wright, P., Heinsen, H., Jones, D. K., Aggleton, J. P. and O'Sullivan, M. J. (2015). Cholinergic basal forebrain structure influences the reconfiguration of white matter connections to support residual memory in Mild Cognitive ImpairmentJournal of Neuroscience, 35(2), 739-747. (10.1523/JNEUROSCI.3617-14.2015) pdf

Steventon, J., Harrison, D. J., Trueman, R. C., Rosser, A. E., Jones, D. K. and Brooks, S. P. (2015). In Vivo MRI evidence that neuropathology is attenuated by cognitive enrichment in the Yac128 Huntington's Disease mouse modelJournal of Huntington's Disease, 4(2), 149-160. (10.3233/JHD-150147)

Steventon, J., Trueman, R. C., Rosser, A. E. and Jones, D. K. (2015). Robust MR-based approaches to quantifying white matter structure and structure/function alterations in Huntington's diseaseJournal of Neuroscience Methods, 265, 2-12. (10.1016/j.jneumeth.2015.08.027) pdf

2014

Berlot, R., Metzler-Baddeley, C., Jones, D. K. and O'Sullivan, M. (2014). CSF contamination contributes to apparent microstructural alterations in mild cognitive impairmentNeuroImage, 92, 27-35. (10.1016/j.neuroimage.2014.01.031)

Caeyenberghs, K., Powell, H., Thomas, R. H., Brindley, L., Church, C., Evans, J., Muthukumaraswamy, S., Jones, D. and Hamandi, K. (2014). Hyperconnectivity in juvenile myoclonic epilepsy: A network analysisNeuroImage: Clinical, 7, 98-104. (10.1016/j.nicl.2014.11.018)

Chantiluke, K., Christakou, A., Murphy, C. M., Giampietro, V., Daly, E. M., Ecker, C., Brammer, M., Murphy, D. G., Rubia, K. and Jones, D. (2014). Disorder-specific functional abnormalities during temporal discounting in youth with Attention Deficit Hyperactivity Disorder (ADHD), Autism and comorbid ADHD and AutismPsychiatry Research: Neuroimaging, 223(2), 113. (10.1016/j.pscychresns.2014.04.006)

Cooper, M., Thapar, A. and Jones, D. (2014). Erratum to: White matter microstructure predicts autistic traits in Attention-Deficit/Hyperactivity DisorderJournal of Autism and Developmental Disorders, 44(11), 2755. (10.1007/s10803-014-2162-2)

Cooper, M., Thapar, A. and Jones, D. K. (2014). White matter microstructure predicts autistic traits in attention-deficit/hyperactivity disorderJournal of Autism and Developmental Disorders, 44(11), 2742-2754. (10.1007/s10803-014-2131-9) pdf

De Santis, S., Assaf, Y., Evans, C. J. and Jones, D. K. (2014). Improved precision in CHARMED assessment of white matter through sampling scheme optimization and model parsimony testingMagnetic Resonance in Medicine, 71(2), 661-671. (10.1002/mrm.24717)

De Santis, S., Drakesmith, M., Bells, S., Assaf, Y. and Jones, D. K. (2014). Why diffusion tensor MRI does well only some of the time: Variance and covariance of white matter tissue microstructure attributes in the living human brainNeuroImage, 89, 35-44. (10.1016/j.neuroimage.2013.12.003) pdf

Metzler-Baddeley, C., Cantera, J., Coulthard, E., Rosser, A. E., Jones, D. K. and Baddeley, R. J. (2014). Improved executive function and callosal white matter microstructure after rhythmn exercise in Huntington's diseaseJournal of Huntington's Disease, 3(3), 273-283. (10.3233/JHD-140113)

Postans, M., Hodgetts, C. J., Mundy, M. E., Jones, D. K., Lawrence, A. D. and Graham, K. S. (2014). Individual variation in fornix microstructure and macrostructure is related to visual discrimination accuracy for scenes but not facesJournal of Neuroscience, 34(36), 12121-12126. (10.1523/JNEUROSCI.0026-14.2014) pdf

Powell, R., Caeyenberghs, K., Thomas, R. H., Jones, J. D. K. and Hamandi, K. (2014). Hyperconnectivity in JME-a network analysisJournal of Neurology, Neurosurgery & Psychiatry, 85(10) (10.1136/jnnp-2014-309236.5)

2013

Assaf, Y., Alexander, D. C., Jones, D. K., Bizzi, A., Behrens, T. E. J., Clark, C. A., Cohen, Y., Dyrby, T. B., Huppi, P. S., Knoesche, T. R., LeBihan, D., Parker, G. J. M. and Poupon, C. (2013). The CONNECT project: Combining macro- and micro-structureNeuroImage, 80, 273-282. (10.1016/j.neuroimage.2013.05.055)

De Santis, S., Evans, C. J. and Jones, D. K. (2013). RAPID: A routine assurance pipeline for imaging of diffusionMagnetic Resonance in Medicine, 70(2), 490-496. (10.1002/mrm.24465)

De Santis, S., Assaf, Y., Bells, S., Deoni, S. C. and Jones, D. K. (2013). The CONNECT brain atlas of white matter microstructure [Conference Material]Proceedings of the International Society for Magnetic Resonance Imaging, 21, 843-843.

Jeurissen, B., Leemans, A., Tournier, J., Jones, D. K. and Sijbers, J. (2013). Investigating the prevalence of complex fiber configurations in white matter tissue with diffusion magnetic resonance imagingHuman Brain Mapping, 34(11), 2747-2766. (10.1002/hbm.22099)

Jones, D. K. and Linden, D. E. J. (2013). Abstracts of Presentations at the International Conference on Basic and Clinical Multimodal Imaging (BaCI), a Joint Conference of the International Society for Neuroimaging in Psychiatry (ISNIP), the International Society for Functional Source Imaging (ISFSI), the International Society for Bioelectromagnetism (ISBEM), the International Society for Brain Electromagnetic Topography (ISBET), and the EEG and Clinical Neuroscience Society (ECNS), in Geneva, Switzerland, September 5-8, 2013Clinical EEG and Neuroscience, 44(4), E1. (10.1177/1550059413507209)

Jones, D. K., Christiansen, K. Y., Chapman, R. J. and Aggleton, J. (2013). Distinct subdivisions of the cingulum bundle revealed by diffusion MRI fibre tracking: Implications for europsychological investigations.Neuropsychologia, 51(1), 67-78. (10.1016/j.neuropsychologia.2012.11.018) pdf

Metzler-Baddeley, C., Baddeley, R. J., Jones, D. K., Aggleton, J. P. and O'Sullivan, M. (2013). Individual differences in fornix microstructure and body mass indexPLoS ONE, 8(3) (10.1371/journal.pone.0059849) pdf

Parker, G., Marshall, A. D., Rosin, P. L., Drage, N., Richmond, S. and Jones, D. K. (2013). A pitfall in the reconstruction of fibre ODFs using spherical deconvolution of diffusion MRI dataNeuroImage, 65, 433-448. (10.1016/j.neuroimage.2012.10.022)

2012

Anderson, E. J., Jones, D. K., O'Gorman, R. L., Leemans, A., Catani, M. and Husain, M. (2012). Cortical network for gaze control in humans revealed using multimodal MRICerebral Cortex, 22(4), 765-775. (10.1093/cercor/bhr110) pdf

Ben-Amitay, S., Jones, D. K. and Assaf, Y. (2012). Motion correction and registration of high b-value diffusion weighted imagesMagnetic Resonance in Medicine, 67(6), 1694-1702. (10.1002/mrm.23186)

De Santis, S., Assaf, Y. and Jones, D. K. (2012). Using the biophysical CHARMED model to elucidate the underpinnings of contrast in diffusional kurtosis analysis of diffusion-weighted MRIMagnetic Resonance Materials in Physics, Biology and Medicine, 25(4), 267-276. (10.1007/s10334-011-0292-5)

Ecker, C. et al. (2012). Brain Anatomy and Its Relationship to Behavior in Adults With Autism Spectrum Disorder: A Multicenter Magnetic Resonance Imaging StudyArchives of General Psychiatry, 69(2), 195-209. (10.1001/archgenpsychiatry.2011.1251)

Keedwell, P. A., Chapman, R. J., Christiansen, K. Y., Richardson, H., Evans, C. J. and Jones, D. K. (2012). Cingulum white matter in young women at risk of depression: The effect of family history and anhedoniaBiological Psychiatry, 72(4), 296-302. (10.1016/j.biopsych.2012.01.022)

Metzler-Baddeley, C., Jones, D. K., Steventon, J., Westacott, L., Aggleton, J. P. and O'Sullivan, M. (2012). Cingulum microstructure predicts cognitive control in older age and mild cognitive impairmentJournal of Neuroscience, 32(49), 17612-17619. (10.1523/JNEUROSCI.3299-12.2012) pdf

Metzler-Baddeley, C., O'Sullivan, M., Bells, S., Pasternak, O. and Jones, D. K. (2012). How and how not to correct for CSF-contamination in diffusion MRINeuroimage, 59(2), 1394-1403. (10.1016/j.neuroimage.2011.08.043)

Metzler-Baddeley, C., Hunt, S., Jones, D. K., Leemans, A., Aggleton, J. P. and O'Sullivan, M. (2012). Temporal association tracts and the breakdown of episodic memory in mild cognitive impairmentNeurology, 79(23), 2233-2240. (10.1212/WNL.0b013e31827689e8)

Richmond, S. et al. (2012). Detailing patient specific modeling to aid clinical decision-makingLecture Notes in Computational Vision and Biomechanics, 5, 105-131. (10.1007/978-94-007-4552-0_5)

Sundram, F. et al. (2012). White matter microstructural abnormalities in the frontal lobe of adults with antisocial personality disorderCortex, 48(2), 216-229. (10.1016/j.cortex.2011.06.005)

Vos, S. B., Jones, D. K., Jeurissen, B., Viergever, M. A. and Leemans, A. (2012). The influence of complex white matter architecture on the mean diffusivity in diffusion tensor MRI of the human brainNeuroImage, 59(3), 2208-2216. (10.1016/j.neuroimage.2011.09.086)

2011

(2011). Diffusion MRI: theory, methods and applications. Oxford: Oxford University Press.

Blain, C. R. V., Brunton, S., Williams, V. C., Leemans, A., Turner, M. R., Andersen, P. M., Catani, M., Stanton, B. R., Ganesalingham, J., Jones, D. K., Williams, S. C. R., Leigh, P. N. and Simmons, A. (2011). Differential corticospinal tract degeneration in homozygous 'D90A' SOD-1 ALS and sporadic ALSJournal of Neurology, Neurosurgery & Psychiatry, 82(8), 843-849. (10.1136/jnnp.2010.236018)

Edden, R. A. E. and Jones, D. K. (2011). Spatial and orientational heterogeneity in the statistical sensitivity of skeleton-based analyses of diffusion tensor MR imaging dataJournal of Neuroscience Methods, 201(1), 213-219. (10.1016/j.jneumeth.2011.07.025)

Jeurissen, B., Leemans, A., Jones, D. K., Tournier, J. and Sijbers, J. (2011). Probabilistic fiber tracking using the residual bootstrap with constrained spherical deconvolutionHuman Brain Mapping, 32(3), 461-479. (10.1002/hbm.21032)

Jones, D. K. and Leemans, A. (2011). Diffusion tensor imaging. In: Modo, M. and Bulte, J. eds. Magnetic Resonance Neuroimaging: Methods and Protocols, Vol 711. Springer, pp. 127-144. (10.1007/978-1-61737-992-5_6)

Lai, M. et al. (2011). A Behavioral Comparison of Male and Female Adults with High Functioning Autism Spectrum ConditionsPLoS ONE, 6(6) (10.1371/journal.pone.0020835) pdf

Lombardo, M. V., Chakrabarti, B., Bullmore, E. T., Baron-Cohen, S., Bailey, A. J., Bolton, P. F., Carrington, S. J., Daly, E. M., Deoni, S. C., Ecker, C., Happé, F., Henty, J., Jezzard, P., Johnston, P., Jones, D. K., Lai, M. C., Madden, A., Mullins, D., Murphy, C. and Murphy, D. G. M. (2011). Specialization of right temporo-parietal junction for mentalizing and its relation to social impairments in autismNeuroImage, 56(3), 1832-1838. (10.1016/j.neuroimage.2011.02.067)

Metzler-Baddeley, C., Jones, D. K., Belaroussi, B., Aggleton, J. P. and O'Sullivan, M. (2011). Frontotemporal connections in episodic memory and aging: A diffusion MRI tractography studyThe Journal of Neuroscience, 31(37), 13236-13245. (10.1523/JNEUROSCI.2317-11.2011) pdf

Metzler-Baddeley, C., Jones, D. K., Aggleton, J. P. and O'Sullivan, M. (2011). The fornix in ageing and memory decline: a diffusion MRI tractography study [Abstract]Journal of Neurology, 258(S1), 18-18. (10.1007/s00415-011-6026-9)

Vos, S. B., Jones, D. K., Viergever, M. A. and Leemans, A. (2011). Partial volume effect as a hidden covariate in DTI analysesNeuroImage, 55(4), 1566-1576. (10.1016/j.neuroimage.2011.01.048)

2010

Bloemen, O. J. N., Deeley, Q., Sundram, F., Daly, E. M., Barker, G. J., Jones, D. K., van Amelsvoort, T. A. M. J., Schmitz, N., Robertson, D., Murphy, K. C. and Murphy, D. G. M. (2010). White matter integrity in Asperger syndrome: a preliminary diffusion tensor magnetic resonance imaging study in adultsAutism Research, 3(5), 203-213. (10.1002/aur.146)

Ecker, C. et al. (2010). Investigating the predictive value of whole-brain structural MR scans in autism: A pattern classification approachNeuroImage, 49(1), 44-56. (10.1016/j.neuroimage.2009.08.024)

Jones, D. K. (2010). Challenges and limitations of quantifying brain connectivity in vivo with diffusion MRIImaging in Medicine, 2(3), 341-355. (10.2217/iim.10.21)

Jones, D. K. (2010). Precision and Accuracy in Diffusion Tensor Magnetic Resonance ImagingTopics in Magnetic Resonance Imaging, 21(2), 87-99. (10.1097/RMR.0b013e31821e56ac)

Jones, D. K. and Cercignani, M. (2010). Twenty-five pitfalls in the analysis of diffusion MRI dataNMR in Biomedicine, 23(7), 803-820. (10.1002/nbm.1543)

Lombardo, M. et al. (2010). Atypical neural self-representation in autismBrain, 133(2), 611-624. (10.1093/brain/awp306)

Lombardo, M. et al. (2010). Shared Neural Circuits for Mentalizing about the Self and OthersJournal of Cognitive Neuroscience, 22(7), 1623-1635. (10.1162/jocn.2009.21287) pdf

Muthukumaraswamy, S. D., Singh, K. D., Swettenham, J. B. and Jones, D. K. (2010). Visual gamma oscillations and evoked responses: Variability, repeatability and structural MRI correlatesNeuroImage, 49(4), 3349-3357. (10.1016/j.neuroimage.2009.11.045)

Sundram, F., Campbell, L. E., Azuma, R., Daly, E., Bloemen, O. J. N., Barker, G. J., Chitnis, X., Jones, D. K., Amelsvoort, T., Murphy, K. C. and Murphy, D. G. M. (2010). White matter microstructure in 22q11 deletion syndrome: a pilot diffusion tensor imaging and voxel-based morphometry study of children and adolescentsJournal of Neurodevelopmental Disorders, 2(2), 77-92. (10.1007/s11689-010-9043-6)

2009

Jones, D. K. (2009). Fundamentals of diffusion MR imaging. In: Gillard, J., Waldman, A. and Barker, P. eds. Clinical MR Neuroimaging: Physiological and Functional Techniques. 2nd ed.. Cambridge: Cambridge University Press, pp. 44-67.

Jones, D. K. (2009). Gaussian modeling of the diffusion signal. In: Johansen-Berg, H. and Behrens, T. eds. Diffusion MRI: From Quantitative Measurement to In vivo Neuroanatomy. Amsterdam: Elsevier, pp. 37-64. (10.1016/B978-0-12-374709-9.00003-1)

Kanaan, R. A. A., Borgwardt, S., McGuire, P. K., Craig, M. C., Murphy, D. G. M., Picchioni, M., Shergill, S. S., Jones, D. K. and Catani, M. (2009). Microstructural Organization of Cerebellar Tracts in SchizophreniaBiological Psychiatry, 66(11), 1067-1069. (10.1016/j.biopsych.2009.07.028)

Kontis, D., Catani, M., Cuddy, M., Walshe, M., Nosarti, C., Jones, D. K., Wyatt, J., Rifkin, L., Murray, R. and Allin, M. (2009). Diffusion tensor MRI of the corpus callosum and cognitive function in adults born pretermNeuroReport, 20(4), 424-428. (10.1097/WNR.0b013e328325a8f9)

Leemans, A. and Jones, D. K. (2009). The B-matrix must be rotated when correcting for subject motion in DTI dataMagnetic Resonance in Medicine, 61(6), 1336-1349. (10.1002/mrm.21890)

Muthukumaraswamy, S. D., Edden, R. A. E., Jones, D. K., Swettenham, J. B. and Singh, K. D. (2009). Resting GABA concentration predicts peak gamma frequency and fMRI amplitude in response to visual stimulation in humansProceedings of the National Academy of Sciences of the United States of America, 106(20), 8356-8361. (10.1073/pnas.0900728106)

2008

Catani, M., Jones, D. K., Daly, E., Embiricos, N., Deeley, Q., Pugliese, L., Curran, S., Robertson, D. and Murphy, D. G. M. (2008). Altered cerebellar feedback projections in Asperger syndromeNeuroImage, 41(4), 1184-1191. (10.1016/j.neuroimage.2008.03.041)

Deoni, S. C. L., Rutt, B. K., Arun, T., Pierpaoli, C. and Jones, D. K. (2008). Gleaning Multicomponent T-1 and T-2 Information From Steady-State Imaging DataMagnetic Resonance in Medicine, 60(6), 1372-1387. (10.1002/mrm.21704)

Deoni, S. C. L., Williams, S. C., Jezzard, P., Suckling, J., Murphy, D. G. M. and Jones, D. K. (2008). Standardized Structural Magnetic Resonance Imaging in Multicenter Studies using Quantitative T1 and T2 Imaging at 1.5TNeuroImage, 40(2), 662-671. (10.1016/j.neuroimage.2007.11.052)

Jones, D. K. (2008). Studying connections in the living human brain with diffusion MRICortex, 44(8), 936-952. (10.1016/j.cortex.2008.05.002)

Jones, D. K. (2008). Tractography gone wild: Probabilistic fibre tracking using the wild bootstrap with diffusion tensor MRIIEEE Transactions on Medical Imaging, 27(9), 1268-1274. (10.1109/TMI.2008.922191)

2007

Blain, C. R. V., Williams, V. C., Johnston, C., Stanton, B. R., Ganesalingam, J., Jarosz, J. M., Jones, D. K., Barker, G. J., Williams, S. C. R., Leigh, N. P. and Simmons, A. (2007). A longitudinal study of diffusion tensor MRI in ALSAmyotrophic Lateral Sclerosis, 8(6), 348-355. (10.1080/17482960701548139)

Catani, M., Allin, M. P. G., Husain, M., Pugliese, L., Mesulam, M. M., Murray, R. M. and Jones, D. K. (2007). Symmetries in human brain language pathways correlate with verbal recallProceedings of the National Academy of Sciences of the United States of America, 104(43), 17163-17168. (10.1073/pnas.0702116104)

Deoni, S. C. L., Rutt, B. K. and Jones, D. K. (2007). Investigating the effect of exchange and multicomponentT1 relaxation on the short repetition time spoiled steady-state signal and the DESPOT1T1 quantification methodJournal of Magnetic Resonance Imaging, 25(3), 570-578. (10.1002/jmri.20836)

Freidlin, R. Z., Ozarslan, E., Komlosh, M. E., Chang, L. C., Koay, G. C. and Jones, D. K. (2007). Parsimonious model selection for tissue segmentation and classification: study on simulated and experimental DTI dataIEEE Transactions on Medical Imaging, 26(11), 1576-1584. (10.1109/TMI.2007.907294)

Shergill, S. S., Kanaan, R. A. A., Chitnis, X. A., O'Daly, O., Jones, D. K., Frangou, S., Williams, S. C. K., Howard, R. J., Barker, G. J., Murray, R. M. and McGuire, P. (2007). A diffusion tensor imaging study of fasciculi in schizophreniaAmerican Journal of Psychiatry, 164(3), 467-473. (10.1176/appi.ajp.164.3.467) pdf

2006

Blain, C. R. V., Barker, G. J., Jarosz, J. M., Coyle, N. A., Landau, S., Brown, R. G., Chaudhuri, K. R., Simmons, A., Jones, D. K., Williams, S. C. R. and Leigh, P. N. (2006). Measuring brain stem and cerebellar damage in parkinsonian syndromes using diffusion tensor MRINeurology, 67(12), 2199-2205. (10.1212/01.wnl.0000249307.59950.f8)

Jones, D. K., Catani, M., Pierpaoli, C., Reeves, S. J. C., Shergill, S. S., O'Sullivan, M., Golesworthy, P., McGuire, P., Horsfield, M. A., Simmons, A., Williams, S. C. R. and Howard, R. J. (2006). Age effects on diffusion tensor magnetic resonance imaging tractography measures of frontal cortex connections in schizophreniaHuman Brain Mapping, 27(3), 230-238. (10.1002/hbm.20179)

Kanaan, R. A., Shergill, S. S., Barker, G. J., Catani, M., Ng, V. W., Howard, R., McGuire, P. K. and Jones, D. K. (2006). Tract-specific anisotropy measurements in diffusion tensor imagingPsychiatry Research: Neuroimaging, 146(1), 73-82. (10.1016/j.pscychresns.2005.11.002)

O'Gorman, R. L. and Jones, D. K. (2006). Just how much data need to be collected for reliable bootstrap DT-MRI?Magnetic Resonance in Medicine, 56(4), 884-890. (10.1002/mrm.21014)

Turner, M. R., Williams, V., Jones, D. K. and Leigh, P. N. (2006). Neuroimaging in amyotrophic lateral sclerosis. In: Brown, R., Swash, M. and Pasinelli, P. eds. Amyotrophic Lateral Sclerosis (2nd ed.). Abingdon: Informa Healthcare, pp. 45-68.

2005

Catani, M., Jones, D. K. and Ffytche, D. H. (2005). Perisylvian language networks of the human brainAnnals of Neurology, 57(1), 8-16. (10.1002/ana.20319)

Chang, L., Jones, D. K. and Pierpaoli, C. (2005). RESTORE: Robust estimation of tensors by outlier rejectionMagnetic Resonance in Medicine, 53(5), 1088-1095. (10.1002/mrm.20426)

Daurignac, E., Toga, A. W., Jones, D. K., Aronen, H. J., Hommer, D. W., Jernigan, T. L., Krystal, J. H. and Mathalon, D. H. (2005). Applications of Morphometric and Diffusion Tensor Magnetic Resonance Imaging to the Study of Brain Abnormalities in the Alcoholism SpectrumAlcoholism: Clinical & Experimental Research, 29(1), 159-166. (10.1097/01.ALC.0000150891.72900.62)

Jones, D. K., Catani, M., Pierpaoli, C., Reeves, S. J., Shergill, S. S., O'Sullivan, M., Maguire, P., Horsfield, M. A., Simmons, A., Williams, S. C. and Howard, R. J. (2005). A diffusion tensor magnetic resonance imaging study of frontal cortex connections in very-late-onset schizophrenia-like psychosisAmerican Journal of Geriatric Psychiatry, 13(12), 1092-1099. (10.1176/appi.ajgp.13.12.1092)

Jones, D. K., Catani, M., Pierpaoli, C., Reeves, S. J., Shergill, S. S., O'Sullivan, M., Maguire, P., Horsfield, M. A., Simmons, A., Williams, S. C. and Howard, R. J. (2005). A diffusion tensor magnetic resonance imaging study of frontal cortex connections in very late-onset schizophrenia-like psychosisAmerican Journal of Geriatric Psychiatry, 13(12), 1092-1099.

Jones, D. K. and Pierpaoli, C. (2005). Confidence mapping in diffusion tensor magnetic resonance imaging tractography using a bootstrap approachMagnetic Resonance in Medicine, 53(5), 1143-1149. (10.1002/mrm.20466)

Jones, D. K., Travis, A. R., Eden, G., Pierpaoli, C. and Basser, P. J. (2005). PASTA: Pointwise assessment of streamline tractography attributesMagnetic Resonance in Medicine, 53(6), 1462-1467. (10.1002/mrm.20484)

Jones, D. K., Symms, M. R., Cercignani, M. and Howard, R. J. (2005). The Effect of Filter Size on the Outcome of VBM Analyses of DT-MRI DataNeuroImage, 26(2), 546-554. (10.1016/j.neuroimage.2005.02.013)

2004

Jones, D. K. and Basser, P. J. (2004). "Squashing peanuts and smashing pumpkins": How noise distorts diffusion-weighted MR dataMagnetic Resonance in Medicine, 52(5), 979-993. (10.1002/mrm.20283)

Jones, D. K. (2004). Fundamentals of diffusion MR imaging. In: Gillard, J., Waldman, A. and Barker, P. eds. Clinical MR Neuroimaging: Diffusion, Perfusion and Spectroscopy. Cambridge: Cambridge University Press, pp. 54-85. (10.1017/CBO9780511544958.006)

Jones, D. K. (2004). The effect of gradient sampling schemes on measures derived from diffusion tensor MRI: A Monte Carlo studyMagnetic Resonance in Medicine, 51(4), 807-815. (10.1002/mrm.20033)

O'Sullivan, M., Morris, R. G., Huckstep, B., Jones, D. K., Williams, S. C. R. and Markus, H. S. (2004). Diffusion tensor MRI correlates with executive dysfunction in patients with ischaemic leukoaraiosisJournal of Neurology, Neurosurgery and Psychiatry, 75(3), 441-447. (10.1136/jnnp.2003.014910)

2003

Catani, M., Jones, D. K., Donato, R. and Ffytche, D. H. (2003). Occipito-temporal connections in the human brainBrain, 126(9), 2093-2107. (10.1093/brain/awg203)

Jones, D. K. (2003). Determining and visualizing uncertainty in estimates of fiber orientation from diffusion tensor MRIMagnetic Resonance in Medicine, 49(1), 7-12. (10.1002/mrm.10331)

2002

Basser, P. J. and Jones, D. K. (2002). Diffusion-tensor MRI: theory, experimental design and data analysis - a technical reviewNMR in Biomedicine, 15(7-8), 456-467. (10.1002/nbm.783)

Catani, M., Howard, R. J., Pajevic, S. and Jones, D. K. (2002). Virtual in vivo interactive dissection of white matter fasciculi in the human brainNeuroimage, 17(1), 77-94. (10.1006/nimg.2002.1136)

Horsfield, M. A. and Jones, D. K. (2002). Applications of diffusion-weighted and diffusion tensor MRI to white matter diseases - a reviewNMR in Biomedicine, 15(7-8), 570-577. (10.1002/nbm.787)

Jones, D. K., Williams, S. C. R., Gasston, D., Horsfield, M. A., Simmons, A. and Howard, R. (2002). Isotropic resolution diffusion tensor imaging with whole brain acquisition in a clinically acceptable timeHuman Brain Mapping, 15(4), 216-230. (10.1002/hbm.10018)

Jones, D. K., Griffin, L. D., Alexander, D. C., Catani, M., Horsfield, M. A., Howard, R. and Williams, S. C. R. (2002). Spatial normalisation and averaging of diffusion tensor MRI data setsNeuroImage, 17(2), 592-617. (10.1016/S1053-8119(02)91148-1)

Taber, K. H., Pierpaoli, C., Rose, S. E., Rugg-Gunn, F. J., Chalk, J. B., Jones, D. K. and Hurley, R. A. (2002). The future for diffusion tensor imaging in neuropsychiatryThe Journal of Neuropsychiatry & Clinical Neurosciences, 14(1), 1-5.

2001

O'Sullivan, M., Jones, D. K., Summers, P. E., Morris, R. G., Williams, S. C. R. and Markus, H. S. (2001). Evidence for cortical "disconnection" as a mechanism of age-related cognitive declineNeurology, 57(4), 632-638. (10.1212/WNL.57.4.632)

O'Sullivan, M., Summers, P. E., Jones, D. K., Jarosz, J. M., Williams, S. C. R. and Markus, H. S. (2001). Normal-appearing white matter in ischemic leukoaraiosis: A diffusion tensor MRI studyNeurology, 57(12), 2307-2310. (10.1212/WNL.57.12.2307)

Rose, S. E., Chalk, J. B., Griffin, M. P., Janke, A. L., Chen, F., McLachan, G. J., Peel, D., Zelaya, F. O., Markus, H. S., Jones, D. K., Simmons, A., O'Sullivan, M., Jarosz, J. M., Strugnell, W., Doddrell, D. M. and Semple, J. (2001). MRI based diffusion and perfusion predictive model to estimate stroke evolutionMagnetic Resonance Imaging, 19(8), 1043-1053. (10.1016/S0730-725X(01)00435-0)

2000

Jones, D. K., Dardis, R., Ervine, M., Horsfield, M. A., Jeffree, M., Simmons, A., Jarosz, J. and Strong, A. J. (2000). Cluster analysis of diffusion tensor magnetic resonance images in human head injuryNeurosurgery, 47(2), 306-314.

1999

Ellis, C. M., Simmons, A., Jones, D. K., Bland, J., Dawson, J. M., Horsfield, M. A., Williams, S. C. R. and Leigh, P. N. (1999). Diffusion tensor MRI assesses corticospinal tract damage in ALSNeurology, 53(5), 1051-1058. (10.1212/WNL.53.5.1051)

Jones, D. K., Lythgoe, D., Horsfield, M. A., Simmons, A., Williams, S. C. R. and Markus, H. S. (1999). Characterization of white matter damage in ischemic leukoaraiosis with diffusion tensor MRIStroke, 30(2), 393-397. (10.1161/01.STR.30.2.393) pdf

Jones, D. K., Simmons, A., Williams, S. C. R. and Horsfield, M. A. (1999). Non-invasive assessment of axonal fiber connectivity in the human brain via diffusion tensor MRIMagnetic Resonance in Medicine, 42(1), 37-41. (10.1002/(SICI)1522-2594(199907)42:1<37::AID-MRM7>3.0.CO;2-O)

Jones, D. K., Horsfield, M. A. and Simmons, A. (1999). Optimal strategies for measuring diffusion in anisotropic systems by magnetic resonance imagingMagnetic Resonance in Medicine, 42(3), 515-525. (10.1002/(SICI)1522-2594(199909)42:3<515::AID-MRM14>3.0.CO;2-Q)

Simmons, A., Jones, D. K., Horsfield, M. A. and Williams, S. C. R. (1999). Application of diffusion tensor MRI to neurological segmentationInternational Journal of Imaging Systems and Technology, 10(3), 273-286. (10.1002/(SICI)1098-1098(1999)10:3<273::AID-IMA8>3.0.CO;2-E)

Wilcock, D. J., Jones, D. K., Horsfield, M. A. and Cherryman, G. R. (1999). Echoplanar MRI in patients with an acute stroke syndromeBritish Journal of Radiology, 72(861), 914-921.

1998

Horsfield, M. A., Larsson, H. B. W., Jones, D. K. and Gass, A. (1998). Diffusion magnetic resonance imaging in multiple sclerosisJournal of Neurology, Neurosurgery and Psychiatry, 64(S), S80-S84.

Research topics and related papers

Optimal design of MR acquisition schemes for quantitative assessment of white matter.

Statistical methods for analysing individual and grouped DT-MRI data sets

Development of fiber tractography – algorithms and visualization techniques

Combination of rapid relaxometric measurements with diffusion imaging data.

Applications of DT-MRI tractography to the study of diseased populations

Integration of white matter structural assessment with other modalities (MEG, TMS, FMRI)

Funding

“Tractometry” 
Type: 
Wellcome Trust Investigator Award
Principal Investigator:  Jones DK
Start Date: May 2012
Duration: 84 months
Agency
: The Wellcome Trust
Budget: £1 700 000

Toward Robust Statistical Comparisons of White Matter Tracts in the Human Brain” (067437/Z/02/A)
Type: Advanced Training Fellowship
Principal Investigator: DK Jones
Start: 01/08/03
Duration: 36 months
Agency: Wellcome Trust, UK
Budget: £290,000

Imaging the Deaf Brain: Functional and Structural Studies Using MRI” (GR068607MA)
Type: Project Grant
Principal Investigator: R Campbell
Co-Investigators: B Woll, MJ Brammer, AS David, M McSweeney, DK Jones
Start: 01/03/04
Duration: 36 months
Agency: Wellcome Trust, UK
Budget: £422,000.

Brain Anatomy in Autism; a Multi-Centre Study” (G0400061)
Type: Strategic Grant
Principal Investigator: DGM Murphy
Co-Investigators: S Baron-Cohen, PF Bolton, M Brammer, E Bullmore, S Curran, FG Happé, P Jezzard, DK Jones, SCR Williams
Start: 01/06/05
Duration: 48 months
Agency: Medical Research Council, UK
Budget: £641,000.

“Brain Anatomy and Connectivity: an Endophenotype in Autism Spectrum Disorders”
Type: Pilot Research Study
Principal Investigator: DGM Murphy
Co-Investigators: DK Jones DK, ET Bullmore,  FG Happé, FV Rijsdijk,  PF Bolton, M Catani, S Baron-Cohen, S Curran, SCR Williams
Start: 10/02/06
Duration: 24 months
Agency: Cure Autism Now Foundation (now merged with Autism Speaks, with head office here:  Autism Speaks, 2 Park Avenue, 11th Floor, New York, NY 10016, USA)
Budget: $120,000.

“The Genetic and Environmental Determinants of Brain Development and Social Function: a Twin Study of Autistic Spectrum Disorder
Type: Pilot Research Study
Principal Investigator: DGM Murphy
Co-Investigators: DK Jones, ET Bullmore, FG Happé, FV Rijsdijk, PF Bolton, M Catani, S Baron-Cohen, S Curran, SCR Williams
Start: 01/03/06
Duration: 24 months
Agency: Autism Speaks
Budget: £60,000.

“Cerebral Mechanisms Underlying Cognitive Dysfunction in Amyotrophic Lateral Sclerosis” (WT083477AIA) 
Type: Project Grant
Principal Investigator: Goldstein L
Co-Investigators: Jones DK, Landau S, Catani M, Leigh PN, Williams SCR
Start: 01/03/08
Duration: 36 months
Agency: Wellcome Trust, UK
Budget: £212,246.

“Imaging the Maternal Brain Following Pregnancy”
Type: Pilot Grant
Principal Investigator: Jones DK. 
Duration: 12 months
Start Date: 01/08/08
Agency: The Waterloo Foundation, UK
Budget: £29,012

“CONNECT: Consortium of Neuroimagers for Non-Invasive Exploration of Connectivity and Tracts”
Type: FP7 - FET Grant
Duration: 24 months
Start Date: 01/10/09
Agency: The European Council, FP7, UK
Budget: Î2,500,000.

“Cerebral small vessel disease, blunted perfusion responses and adaptation to early Alzheimer’s disease’
Type: Pilot Grant
Principal Investigator: O’Sullivan M
Co-Investigators: Wise, RG, Bayer A, Jones DK
Duration:
18 months
Start Date: 01/08/09
Agency: Alzheimer’s Research Trust;  UK
Budget: £26,950

“The role of white matter microstructure in normal cognition”
Type:  Project Grant
Principal Investigator:  Jones DK
Co-Investigator: Assaf Y
Start Date: 01/11/09
Duration:  12 months
Agency: The British Council
Budget: £29,951

“Characterizing the functional and anatomical integrity of visual attention-related processing in Alzheimer's disease and vascular cognitive impairment using magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) techniques.”
Type:  Project Grant
Principal Investigator:  Tales A
Co-Investigators: Bayer T, Singh K, Jones DK, O’Sullivan M
Start Date: tbc
Duration:  24 months
Agency: BRACE
Budget: £164, 702

“Integrated Brain Imaging and Stimulation Project (IBIS)”
Type: Collaborative Industrial Research Project (CIRP)
Principal Investigator:  Chambers C
Co-Investigators: Singh K,Jones DK, Wise RG, Jiles D
Start Date: tbc
Agency: Welsh Assembly Government
Budget: £477, 101.      

“Advanced neuroimaging in BECCTS”
Type:  Project Grant
Principal Investigator:  Hamandi K
Co-Investigators: Jones DK, Singh K, Wise RG, McGonigle DM, Muthukumaraswamy S
Start Date: 01/12/09
Duration: 24 months
Agency: The Waterloo Foundation
Budget: £110, 000.     

“Structural brain correlates of an operationally defined high-risk phenotype for schizophrenia: a population based study”
Type:  Project Grant
Principal Investigator:  David A
Co-Investigators: Blair P, Jones DK, Jones PB, Lewis G, McGuire P, Reichenberg A, Zammit S
Start Date: 01/04/10
Duration: 36 months
Agency: Medical Research Council, UK
Budget: £1,090,153

Cardiff University International Distinguished Visitor Award, £1,880

Research group

Sonya Bells
Luke Dustan
Greg Parker
Bonni Crawford

Postgraduate research interests

My research is focussed on imaging of brain structure both at the macro- and micro-structural level. I am interested in how we may predict brain function from quantitative assessment of brain structure, particularly of the white matter which forms the connections between different brain regions. Without a detailed understanding of the connections and connectivity of the brain, we cannot fully understand how the brain functions. Yet this is an area largely overlooked in cognitive neuroscience. My research looks to fill these gaps in our knowledge. I employ a range of techniques including diffusion tensor imaging, relaxometry, volumetry and magnetization transfer imaging and combine these measures with assessment of brain function using both traditional cognitive tests and state-of-the-art neuroimaging methods to assess brain function, including functional MRI, magnetoencephalography (MEG) and transcranial magnetic stimulation (TMS).

Opportunities for research cover all parts of the spectrum from basic methods development (suited to the more technically oriented), through to pure applications-driven research applying these methods to the study of the healthy and diseased brain.

If you are interested in applying for a PhD, or for further information regarding my postgraduate research, please contact me directly (contact details available on the 'Overview' page), or submit a formal application here.

Current students

Sonya Bells
Marco Catani (Institute of Psychiatry, Kings College London)
Miriam Cooper
Luke Dustan
Greg Parker
Jess Steventon

Undergraduate education

1993:  B.Sc. (Hons) in Physics, (First Class). University of Nottingham, UK

Postgraduate education

1995:  M.Sc. in Medical Physics. University of Leeds, UK

1995: Post Graduate Diploma of the Institute of Physical Sciences in Medicine

1998: Ph.D., “Diffusion Tensor Magnetic Resonance Imaging in the Human Central Nervous System”, University of Leicester, UK

Awards/external committees

AWARDS

ISMRM Outstanding Teacher Award, 2009.

ISMRM Outstanding Teacher Award, 2008.

ISMRM Outstanding Teacher Award, 2007.

ISMRM Art and Artefacts Award, 3rd place, 2007.

ISMRM Outstanding Teacher Award, 2006.

ISMRM Outstanding Teacher Award, 2005.

Finalist in the ISMRM Young Investigator Awards (3 scientists in final), 2004.

Fellows Award for Research Excellence (FARE), National Institutes of Health, 2003.

Student Travel Award, ISMRM, (1998, 2002).

COMMITTEE/ BOARD MEMBERSHIP AND ASSOCIATED ACTIVITIES

Wellcome Trust Neuroscience and Mental Health Board Funding Committee 2008 –

Board of Trustees of International Society for Magnetic Resonance in Medicine 2008 –

Chair of Publications Committee, ISMRM, 2010 –

Chair of ISMRM Diffusion/Perfusion Study Group 2008-

Chair of Audit Committee, ISMRM, 2008 –

Committee of British Chapter of the ISMRM, 2008 –

Executive Board for ISMRM White Matter Study Group 2008-

Editorial Board MAGMA, 2009-

Editorial Board of NeuroImage, 2005-2008.          

ISMRM Scientific Program and Education Committee, 2005-2008. 

ISMRM Educational Coordinator for Diffusion, Perfusion and FMRI, 2006-2008.         

Chair of ISMRM Diffusion/Perfusion Study Group 2005-2006 (640+ members).

ISMRM Study Group Review Committee, 2005-2007.

EPSRC Peer Review College Member, 2003 –

Chair Elect for ISMRM Diffusion/Perfusion Study Group 2004-2005.

Review Panel for International Society for Magnetic Resonance in Medicine, 2002-

ISMRM Teaching Faculty, 2002-

Chair of Organizing Committee for British Chapter of the ISMRM (2009)

Chair of Organizing Committee for ESMRMB ‘Lectures on Diffusion’, Cardiff (2008)

Organizing committee for ISMRM workshop on ‘Quantitative Diffusion MRI in the Human Brain’, Chateau Lake Louise, Banff, Canada, March 2005.

Organizer of ISMRM 2006 Weekend Educational Course on Diffusion/Perfusion MRI.

Originator/Co-ordinator of UK Diffusion Methods Interest Group, (50+ attendees).

Initiated, obtained funding for, and organized a Bi-National Workshop on “MRI of Brain Connectivity and Microstructure” under the SNDS scheme of the Office of Science and Technology and Israeli Ministry of Science.

Employment

2006 - present: Full Professor and Director of MRI, CUBRIC, Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Cardiff, UK.

2003 – 2006: Senior Lecturer and Wellcome Advanced Fellow, Neuroimaging Research Dept., Institute of Psychiatry, Kings College London, UK

2002 – 2004: Visiting Research Fellow, National Institutes of Health (NIH), National Institute of Child Health and Human Development, Bethesda, Maryland, USA

2001 – 2002: Research Physicist, Neuroimaging Research Dept., Kings College, London, UK

1999 – 2001: Research Worker, Old Age Psychiatry, Institute of Psychiatry, London, UK

1995 – 1998: Research Assistant, Medical Physics Department, University of Leicester, UK

1993 – 1995: Medical Physicist, Division of Medical Physics, Leicester Royal Infirmary, UK