School of Psychology Contacts & people

Professor Chris Chambers BSc PhD CPsychol FBPsS

Head of Brain Stimulation, CUBRIC

Research groups:
Neuroscience
Cognitive Science
Email:
ChambersC1@cardiff.ac.uk
Telephone:
+44(0)29 2087 0331
Location:
Tower Building, Park Place

Research summary

My principal research interests include the use of transcranial magnetic stimulation (TMS) and brain imaging techniques (fMRI, DTI, MRS, MEG) to understand neural mechanisms of selective attention, awareness and cognitive control in the human brain. My group is also pursuing the simultaneous combination of TMS, MRI and electroencephalography (EEG), as well as technical advances in TMS methods to improve the precision and reliability of cortical stimulation.

Teaching summary

Academic Teaching

Level 1 Psychology: ‘Magnetic stimulation of the human brain in psychology and neuroscience’ (2009-)

Level 3 Psychology: ‘Methods and applications of transcranial magnetic stimulation’ (2010-)

MSc in Neuroimaging Methods and Applications (2011-)

Professional Workshops

ARC Centre for Excellence, Macquarie University, Australia –  ‘Workshop on basic research with transcranial magnetic stimulation (TMS)’ (2011)

MARCS Auditory Laboratories, University of Western Sydney, Australia – ‘Introduction to transcranial magnetic stimulation’ (2011)

Marie Curie FP7 Advanced Training Course, U.K., ‘Applications of transcranial magnetic stimulation in cognitive neuroscience’ (2010)

CUBRIC, Wales Institute of Cognitive Neuroscience (WICN) Summer School – ‘Introduction to TMS’ and two-day practical workshop (2009)

Psychology Department, University of California San Diego – ‘Introduction to theory and practice of TMS’  (2007)

Magstim TMS Summer School – ‘Practical Introduction to TMS’ (2007)

Dartmouth Summer Institute in Cognitive Neuroscience – ‘Introduction to TMS’ (2006)

Selected publications (2008 onwards)

2014

Allen, C., Dunkley, B., Muthukumaraswamy, S., Edden, R., Evans, C. J., Sumner, P., Singh, K. and Chambers, C. (2014). Enhanced awareness followed reversible inhibition of human visual cortex: a combined TMS, MRS and MEG studyPLoS ONE, 9(6), e100350. (10.1371/journal.pone.0100350) pdf

Allen, C. P. G., Sumner, P. and Chambers, C. D. (2014). The timing and neuroanatomy of conscious vision as revealed by TMS-induced blindsightJournal of Cognitive Neuroscience (10.1162/jocn_a_00557) pdf

Chambers, C. D., Feredoes, E., Muthukumaraswamy, S. D. and Etchells, P. (2014). Instead of "playing the game" it is time to change the rules: Registered Reports at AIMS Neuroscience and beyondAIMS Neuroscience, 1(1), 4-17. (10.3934/Neuroscience2014.1.4) pdf

Verbruggen, F., Stevens, T. and Chambers, C. D. (2014). Proactive and reactive stopping when distracted: an attentional accountJournal of Experimental Psychology: Human Perception and Performance (10.1037/a0036542) pdf

2013

Chambers, C. D., Allen, C. P. G., Maizey, L. and Williams, M. A. (2013). Is delayed foveal feedback critical for extra-foveal perception?Cortex, 49(1), 327-335. (10.1016/j.cortex.2012.03.007) pdf

Chambers, C. D. (2013). Registered Reports: A new publishing initiative at Cortex [Editorial]Cortex, 49(3), 609-610. (10.1016/j.cortex.2012.12.016) pdf

Cummins, T. D. R., Jacoby, O., Hawi, Z., Nandam, L. S., Byrne, M. A. V., Kim, B., Wagner, J., Chambers, C. D. and Bellgrove, M. A. (2013). Alpha-2A adrenergic receptor gene variants are associated with increased intra-individual variability in response timeMolecular Psychiatry (10.1038/mp.2013.140)

Maizey, L., Allen, C. P. G., Dervinis, M., Verbruggen, F., Varnava, A., Kozlov, M. D., Adams, R. C., Stokes, M., Klemen, J., Bungert, A., Hounsell, C. A. and Chambers, C. D. (2013). Comparative incidence rates of mild adverse effects to transcranial magnetic stimulationClinical Neurophysiology, 124(3), 536-544. (10.1016/j.clinph.2012.07.024) pdf

Rusconi, E., Dervinis, M., Verbruggen, F. and Chambers, C. D. (2013). Critical Time Course of Right Frontoparietal Involvement in Mental Number SpaceJournal of Cognitive Neuroscience, 25(3), 465-483. (10.1162/jocn_a_00330) pdf

Stokes, M. G., Barker, A. T., Dervinis, M., Verbruggen, F., Maizey, L., Adams, R. C. and Chambers, C. D. (2013). Biophysical determinants of transcranial magnetic stimulation: Effects of excitability and depth of targeted areaJournal of Neurophysiology, 109(2), 437-444. (10.1152/jn.00510.2012)

Varnava, A., Dervinis, M. and Chambers, C. D. (2013). The predictive nature of pseudoneglect for visual neglect: Evidence from parietal theta burst stimulationPlos One, 8(6) (10.1371/journal.pone.0065851) pdf

Verbruggen, F., Adams, R. C., Van't Wout, F., Stevens, T., McLaren, I. and Chambers, C. D. (2013). Are the effects of response inhibition on gambling long-lasting?PLoS ONE, 8(7) (10.1371/journal.pone.0070155) pdf

Verbruggen, F., Chambers, C. D. and Logan, G. (2013). Fictitious inhibitory differences: How skewness and slowing distort the estimation of stopping latenciesPsychological Science, 24(3), 352-362. (10.1177/0956797612457390) pdf

2012

Adams, R. C. and Chambers, C. D. (2012). Mapping the timecourse of goal-directed attention to location and colour in human visionActa Psychologica, 139(3), 515-523. (10.1016/j.actpsy.2012.01.014)

Bungert, A., Chambers, C. D., Long, E. and Evans, C. J. (2012). On the importance of specialized radiofrequency filtering for concurrent TMS/MRIJournal of Neuroscience Methods, 210(2), 202-205. (10.1016/j.jneumeth.2012.07.023)

Bungert, A., Chambers, C. D., Phillips, M. and Evans, C. J. (2012). Reducing image artefacts in concurrent TMS/fMRI by passive shimmingNeuroImage, 59(3), 2167-2174. (10.1016/j.neuroimage.2011.10.013) pdf

Cai, W., George, J. S., Verbruggen, F., Chambers, C. D. and Aron, A. R. (2012). The role of the right pre-supplementary motor area in stopping action: two studies with event-related transcranial magnetic stimulationJournal of Neurophysiology, 108(2), 380-389. (10.1152/jn.00132.2012)

Cai, W., George, J. S., Chambers, C. D., Stokes, M. G., Verbruggen, F. and Aron, A. R. (2012). Stimulating deep cortical structures with the batwing coil: How to determine the intensity for transcranial magnetic stimulation using coil-cortex distanceJournal of Neuroscience Methods, 204(2), 238-241. (10.1016/j.jneumeth.2011.11.020)

Cummins, T. D. R., Hawi, Z., Hocking, J., Strudwick, M., Hester, R., Garavan, H., Wagner, J., Chambers, C. D. and Bellgrove, M. A. (2012). Dopamine transporter genotype predicts behavioural and neural measures of response inhibitionMolecular Psychiatry, 17, 1086-1092. (10.1038/mp.2011.104)

Garner, K. G., Dux, P. E., Wagner, J., Cummins, T. D. R., Chambers, C. D. and Bellgrove, M. A. (2012). Attentional asymmetries in a visual orienting task are related to temperamentCognition & Emotion, 26(8), 1508-1515. (10.1080/02699931.2012.666205)

Klemen, J., Hoffmann, M. B. and Chambers, C. (2012). Cortical plasticity in the face of congenitally altered input into V1Cortex, 48(10), 1362-1365. (10.1016/j.cortex.2012.03.012)

Klemen, J. and Chambers, C. D. (2012). Current perspectives and methods in studying neural mechanisms of multisensory interactionsNeuroscience & Biobehavioral Reviews, 36(1), 111-133. (10.1016/j.neubiorev.2011.04.015)

Verbruggen, F., Adams, R. C. and Chambers, C. D. (2012). Proactive motor control reduces monetary risk taking in gamblingPsychological Science, 23(7), 805-815. (10.1177/0956797611434538) pdf

2011

Baker, K. S., Mattingley, J. B., Chambers, C. D. and Cunnington, R. (2011). Attention and the readiness for actionNeuropsychologia, 49(12), 3303-3313. (10.1016/j.neuropsychologia.2011.08.003)

Heinen, K., Ruff, C. C., Bjoertomt, O., Schenkluhn, B., Bestmann, S., Blankenburg, F., Driver, J. and Chambers, C. D. (2011). Concurrent TMS-fMRI reveals dynamic interhemispheric influences of the right parietal cortex during exogenously cued visuospatial attentionEuropean Journal of Neuroscience, 33(5), 991-1000. (10.1111/j.1460-9568.2010.07580.x)

Klemen, J., Verbruggen, F., Skelton, C. and Chambers, C. D. (2011). Enhancement of perceptual representations by endogenous attention biases competition in response selectionAttention, Perception, & Psychophysics, 73(8), 2514-2527. (10.3758/s13414-011-0188-5)

Kurniawan, V., Klemen, J. and Chambers, C. D. (2011). Microcontroller based fibre-optic visual presentation system for multisensory neuroimagingJournal of Neuroscience Methods, 202(1), 28-37. (10.1016/j.jneumeth.2011.08.033)

Varnava, A., Stokes, M. G. and Chambers, C. D. (2011). Reliability of the 'observation of movement' method for determining motor threshold using transcranial magnetic stimulationJournal of Neuroscience Methods, 201(2), 327-332. (10.1016/j.jneumeth.2011.08.016)

2010

Chambers, C. D. and Heinen, K. (2010). TMS and the functional neuroanatomy of attentionCortex, 46(1), 114-117. (10.1016/j.cortex.2009.03.002)

Verbruggen, F., Aron, A. R., Stevens, M. A. and Chambers, C. D. (2010). Theta burst stimulation dissociates attention and action updating in human inferior frontal cortexProceedings of the National Academy of Sciences, 107(31), 13966-13971. (10.1073/pnas.1001957107)

2009

Bellgrove, M. A., Johnson, K. A., Barry, E., Mulligan, A., Hawi, Z., Gill, M., Robertson, I. and Chambers, C. D. (2009). Dopaminergic haplotype as a predictor of spatial inattention in children with attention-deficit/hyperactivity disorderArchives of General Psychiatry, 66(10), 1135-1142. (10.1001/archgenpsychiatry.2009.120)

Chambers, C. D., Garavan, H. and Bellgrove, M. A. (2009). Insights into the neural basis of response inhibition from cognitive and clinical neuroscienceNeuroscience & Biobehavioral Reviews, 33(5), 631-646. (10.1016/j.neubiorev.2008.08.016)

2008

Chambers, C. D. (2008). A stimulating take on attentionPsychologist, 21(6), 502-505.

Schenkluhn, B., Ruff, C. C., Heinen, K. and Chambers, C. D. (2008). Parietal stimulation decouples spatial and feature-based attentionJournal of Neuroscience, 28(44), 11106-11110. (10.1523/JNEUROSCI.3591-08.2008) pdf

Online publications

Full list of publications

2014

Allen, C., Dunkley, B., Muthukumaraswamy, S., Edden, R., Evans, C. J., Sumner, P., Singh, K. and Chambers, C. (2014). Enhanced awareness followed reversible inhibition of human visual cortex: a combined TMS, MRS and MEG studyPLoS ONE, 9(6), e100350. (10.1371/journal.pone.0100350) pdf

Allen, C. P. G., Sumner, P. and Chambers, C. D. (2014). The timing and neuroanatomy of conscious vision as revealed by TMS-induced blindsightJournal of Cognitive Neuroscience (10.1162/jocn_a_00557) pdf

Chambers, C. D., Feredoes, E., Muthukumaraswamy, S. D. and Etchells, P. (2014). Instead of "playing the game" it is time to change the rules: Registered Reports at AIMS Neuroscience and beyondAIMS Neuroscience, 1(1), 4-17. (10.3934/Neuroscience2014.1.4) pdf

Verbruggen, F., Stevens, T. and Chambers, C. D. (2014). Proactive and reactive stopping when distracted: an attentional accountJournal of Experimental Psychology: Human Perception and Performance (10.1037/a0036542) pdf

2013

Chambers, C. D., Allen, C. P. G., Maizey, L. and Williams, M. A. (2013). Is delayed foveal feedback critical for extra-foveal perception?Cortex, 49(1), 327-335. (10.1016/j.cortex.2012.03.007) pdf

Chambers, C. D. (2013). Registered Reports: A new publishing initiative at Cortex [Editorial]Cortex, 49(3), 609-610. (10.1016/j.cortex.2012.12.016) pdf

Cummins, T. D. R., Jacoby, O., Hawi, Z., Nandam, L. S., Byrne, M. A. V., Kim, B., Wagner, J., Chambers, C. D. and Bellgrove, M. A. (2013). Alpha-2A adrenergic receptor gene variants are associated with increased intra-individual variability in response timeMolecular Psychiatry (10.1038/mp.2013.140)

Maizey, L., Allen, C. P. G., Dervinis, M., Verbruggen, F., Varnava, A., Kozlov, M. D., Adams, R. C., Stokes, M., Klemen, J., Bungert, A., Hounsell, C. A. and Chambers, C. D. (2013). Comparative incidence rates of mild adverse effects to transcranial magnetic stimulationClinical Neurophysiology, 124(3), 536-544. (10.1016/j.clinph.2012.07.024) pdf

Rusconi, E., Dervinis, M., Verbruggen, F. and Chambers, C. D. (2013). Critical Time Course of Right Frontoparietal Involvement in Mental Number SpaceJournal of Cognitive Neuroscience, 25(3), 465-483. (10.1162/jocn_a_00330) pdf

Stokes, M. G., Barker, A. T., Dervinis, M., Verbruggen, F., Maizey, L., Adams, R. C. and Chambers, C. D. (2013). Biophysical determinants of transcranial magnetic stimulation: Effects of excitability and depth of targeted areaJournal of Neurophysiology, 109(2), 437-444. (10.1152/jn.00510.2012)

Varnava, A., Dervinis, M. and Chambers, C. D. (2013). The predictive nature of pseudoneglect for visual neglect: Evidence from parietal theta burst stimulationPlos One, 8(6) (10.1371/journal.pone.0065851) pdf

Verbruggen, F., Adams, R. C., Van't Wout, F., Stevens, T., McLaren, I. and Chambers, C. D. (2013). Are the effects of response inhibition on gambling long-lasting?PLoS ONE, 8(7) (10.1371/journal.pone.0070155) pdf

Verbruggen, F., Chambers, C. D. and Logan, G. (2013). Fictitious inhibitory differences: How skewness and slowing distort the estimation of stopping latenciesPsychological Science, 24(3), 352-362. (10.1177/0956797612457390) pdf

2012

Adams, R. C. and Chambers, C. D. (2012). Mapping the timecourse of goal-directed attention to location and colour in human visionActa Psychologica, 139(3), 515-523. (10.1016/j.actpsy.2012.01.014)

Bungert, A., Chambers, C. D., Long, E. and Evans, C. J. (2012). On the importance of specialized radiofrequency filtering for concurrent TMS/MRIJournal of Neuroscience Methods, 210(2), 202-205. (10.1016/j.jneumeth.2012.07.023)

Bungert, A., Chambers, C. D., Phillips, M. and Evans, C. J. (2012). Reducing image artefacts in concurrent TMS/fMRI by passive shimmingNeuroImage, 59(3), 2167-2174. (10.1016/j.neuroimage.2011.10.013) pdf

Cai, W., George, J. S., Verbruggen, F., Chambers, C. D. and Aron, A. R. (2012). The role of the right pre-supplementary motor area in stopping action: two studies with event-related transcranial magnetic stimulationJournal of Neurophysiology, 108(2), 380-389. (10.1152/jn.00132.2012)

Cai, W., George, J. S., Chambers, C. D., Stokes, M. G., Verbruggen, F. and Aron, A. R. (2012). Stimulating deep cortical structures with the batwing coil: How to determine the intensity for transcranial magnetic stimulation using coil-cortex distanceJournal of Neuroscience Methods, 204(2), 238-241. (10.1016/j.jneumeth.2011.11.020)

Cummins, T. D. R., Hawi, Z., Hocking, J., Strudwick, M., Hester, R., Garavan, H., Wagner, J., Chambers, C. D. and Bellgrove, M. A. (2012). Dopamine transporter genotype predicts behavioural and neural measures of response inhibitionMolecular Psychiatry, 17, 1086-1092. (10.1038/mp.2011.104)

Garner, K. G., Dux, P. E., Wagner, J., Cummins, T. D. R., Chambers, C. D. and Bellgrove, M. A. (2012). Attentional asymmetries in a visual orienting task are related to temperamentCognition & Emotion, 26(8), 1508-1515. (10.1080/02699931.2012.666205)

Klemen, J., Hoffmann, M. B. and Chambers, C. (2012). Cortical plasticity in the face of congenitally altered input into V1Cortex, 48(10), 1362-1365. (10.1016/j.cortex.2012.03.012)

Klemen, J. and Chambers, C. D. (2012). Current perspectives and methods in studying neural mechanisms of multisensory interactionsNeuroscience & Biobehavioral Reviews, 36(1), 111-133. (10.1016/j.neubiorev.2011.04.015)

Verbruggen, F., Adams, R. C. and Chambers, C. D. (2012). Proactive motor control reduces monetary risk taking in gamblingPsychological Science, 23(7), 805-815. (10.1177/0956797611434538) pdf

2011

Baker, K. S., Mattingley, J. B., Chambers, C. D. and Cunnington, R. (2011). Attention and the readiness for actionNeuropsychologia, 49(12), 3303-3313. (10.1016/j.neuropsychologia.2011.08.003)

Heinen, K., Ruff, C. C., Bjoertomt, O., Schenkluhn, B., Bestmann, S., Blankenburg, F., Driver, J. and Chambers, C. D. (2011). Concurrent TMS-fMRI reveals dynamic interhemispheric influences of the right parietal cortex during exogenously cued visuospatial attentionEuropean Journal of Neuroscience, 33(5), 991-1000. (10.1111/j.1460-9568.2010.07580.x)

Klemen, J., Verbruggen, F., Skelton, C. and Chambers, C. D. (2011). Enhancement of perceptual representations by endogenous attention biases competition in response selectionAttention, Perception, & Psychophysics, 73(8), 2514-2527. (10.3758/s13414-011-0188-5)

Kurniawan, V., Klemen, J. and Chambers, C. D. (2011). Microcontroller based fibre-optic visual presentation system for multisensory neuroimagingJournal of Neuroscience Methods, 202(1), 28-37. (10.1016/j.jneumeth.2011.08.033)

Varnava, A., Stokes, M. G. and Chambers, C. D. (2011). Reliability of the 'observation of movement' method for determining motor threshold using transcranial magnetic stimulationJournal of Neuroscience Methods, 201(2), 327-332. (10.1016/j.jneumeth.2011.08.016)

2010

Chambers, C. D. and Heinen, K. (2010). TMS and the functional neuroanatomy of attentionCortex, 46(1), 114-117. (10.1016/j.cortex.2009.03.002)

Verbruggen, F., Aron, A. R., Stevens, M. A. and Chambers, C. D. (2010). Theta burst stimulation dissociates attention and action updating in human inferior frontal cortexProceedings of the National Academy of Sciences, 107(31), 13966-13971. (10.1073/pnas.1001957107)

2009

Bellgrove, M. A., Johnson, K. A., Barry, E., Mulligan, A., Hawi, Z., Gill, M., Robertson, I. and Chambers, C. D. (2009). Dopaminergic haplotype as a predictor of spatial inattention in children with attention-deficit/hyperactivity disorderArchives of General Psychiatry, 66(10), 1135-1142. (10.1001/archgenpsychiatry.2009.120)

Chambers, C. D., Garavan, H. and Bellgrove, M. A. (2009). Insights into the neural basis of response inhibition from cognitive and clinical neuroscienceNeuroscience & Biobehavioral Reviews, 33(5), 631-646. (10.1016/j.neubiorev.2008.08.016)

2008

Chambers, C. D. (2008). A stimulating take on attentionPsychologist, 21(6), 502-505.

Schenkluhn, B., Ruff, C. C., Heinen, K. and Chambers, C. D. (2008). Parietal stimulation decouples spatial and feature-based attentionJournal of Neuroscience, 28(44), 11106-11110. (10.1523/JNEUROSCI.3591-08.2008) pdf

2007

Bellgrove, M. A., Chambers, C. D., Johnson, K. A., Daibhis, A., Daly, M., Hawi, Z., Lambert, D., Gill, M. and Robertson, I. H. (2007). Dopaminergic genotype biases spatial attention in healthy childrenMolecular Psychiatry, 12(8), 786-792. (10.1038/sj.mp.4002022)

Chambers, C. D., Bellgrove, M. A., Gould, I. C., English, T., Garavan, H., McNaught, E., Kamke, M. and Mattingley, J. B. (2007). Dissociable Mechanisms of Cognitive Control in Prefrontal and Premotor CortexJournal of Neurophysiology, 98(6), 3638-3647. (10.1152/jn.00685.2007)

Chambers, C. D., Payne, J. M. and Mattingley, J. B. (2007). Parietal disruption impairs reflexive spatial attention within and between sensory modalitiesNeuropsychologia, 45(8), 1715-1724. (10.1016/j.neuropsychologia.2007.01.001)

Morris, A. P., Chambers, C. D. and Mattingley, J. B. (2007). Parietal stimulation destabilizes spatial updating across saccadic eye movementsProceedings of the National Academy of Sciences, 104(21), 9069-9074. (10.1073/pnas.0610508104)

Stokes, M. G., Chambers, C. D., Gould, I. C., English, T., McNaught, E., McDonald, O. and Mattingley, J. B. (2007). Distance-adjusted motor threshold for transcranial magnetic stimulationClinical Neurophysiology, 118(7), 1617-1625. (10.1016/j.clinph.2007.04.004)

2006

Chambers, C. D., Stokes, M. G., Janko, N. E. and Mattingley, J. B. (2006). Enhancement of visual selection during transient disruption of parietal cortexBrain Research, 1097(1), 149-155. (10.1016/j.brainres.2006.04.084)

Chambers, C. D., Bellgrove, M. A., Stokes, M. G., Henderson, T. R., Garavan, H., Robertson, I. H., Morris, A. P. and Mattingley, J. B. (2006). Executive "Brake Failure" following deactivation of human frontal lobeJournal of Cognitive Neuroscience, 18(3), 444-455. (10.1162/jocn.2006.18.3.444) pdf

2005

Bellgrove, M. A., Chambers, C. D., Vance, A., Hall, N., Karamitsios, M. and Bradshaw, J. L. (2005). Lateralized deficit of response inhibition in early-onset schizophreniaPsychological Medicine, 36(4), 495-505. (10.1017/S0033291705006409) pdf

Chambers, C. D., Mattingley, J. B. and Moss, S. A. (2005). Does selective attention influence the octave illusion?Perception, 34(2), 217-229. (10.1068/p5164) pdf

Chambers, C. D. and Mattingley, J. B. (2005). Neurodisruption of selective attention: insights and implicationsTrends in Cognitive Sciences, 9(11), 542-550. (10.1016/j.tics.2005.09.010)

Chambers, C. D. (2005). Staring in the Eye of Auditory Neglect: Comments on ‘Gaze Direction Modulates Auditory Spatial Deficits in Stroke Patients with Neglect’Cortex, 41(2), 117-120. (10.1016/S0010-9452(08)70886-4)

Stokes, M. G., Chambers, C. D., Gould, I. C., Henderson, T. R., Janko, N. E., Allen, N. B. and Mattingley, J. B. (2005). Simple Metric For Scaling Motor Threshold Based on Scalp-Cortex Distance: Application to Studies Using Transcranial Magnetic StimulationJournal of Neurophysiology, 94(6), 4520-4527. (10.1152/jn.00067.2005)

2004

Chambers, C. D., Payne, J. M., Stokes, M. G. and Mattingley, J. B. (2004). Fast and slow parietal pathways mediate spatial attentionNature Neuroscience, 7(3), 217-218. (10.1038/nn1203)

Chambers, C. D., Stokes, M. G. and Mattingley, J. B. (2004). Modality-Specific Control of Strategic Spatial Attention in Parietal CortexNeuron, 44(6), 925-930. (10.1016/j.neuron.2004.12.009)

Chambers, C. D., Mattingley, J. B. and Moss, S. A. (2004). Reconsidering evidence for the suppression model of the octave illusionPsychonomic Bulletin and Review, 11(4), 642-666. (10.3758/BF03196617)

Chambers, C. D., Mattingley, J. B. and Moss, S. A. (2004). The suppression model remains unsound: A reply to DeutschPsychonomic Bulletin and Review, 11(4), 677-680. (10.3758/BF03196619)

Morris, A. P., Kritikos, A., Berberovic, N., Pisella, L., Chambers, C. D. and Mattingley, J. B. (2004). Prism adaptation and spatial attention: A study of visual search in normals and patients with unilateral neglectCortex, 40(4-5), 703-721. (10.1016/S0010-9452(08)70166-7)

2003

Chambers, C. D. and Brown, M. (2003). Timing accuracy under Microsoft Windows revealed through external chronometryBehavior Research Methods, Instruments & Computers, 35(1), 96-108. (10.3758/BF03195501)

2002

Chambers, C. D., Mattingley, J. B. and Moss, S. A. (2002). The octave illusion revisited: Suppression or fusion between ears?Journal of Experimental Psychology: Human Perception and Performance, 28(6), 1288-1302. (10.1037//0096-1523.28.6.1288)

Media activities

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The Guardian

The Guardian

The Guardian

The New York Times

Research topics and related papers

1. Attention and Awareness

Current team members: Chris Allen, Sinead Morrison, Jemma Sedgmond

Our sensory environment contains a vast quantity of information, only a fraction of which can guide behaviour. Brain mechanisms of attention are crucial for enhancing the processing of stimuli that are behaviourally relevant and for minimising distraction. Within the field of attention, our research focuses on the use of TMS and fMRI (including multivoxel pattern analysis methods) to understand the cognitive neuroscience of attentional control, within and between the sensory modalities of vision and touch. In particular, we are aiming to answer the following questions:

  • How do regions in the frontal and parietal cortex modulate competitive interactions between stimuli in the visual cortex?
  • Do the same mechanisms of top-down attentional control operate within and between sensory modalities? Is there a ‘supramodal’ attention system?
  • Do different regions of the parietal (e.g. IPL, SPL) and frontal cortex (e.g. FEF) exhibit functional specificity for different aspects of attention?
  • Which visual pathways and mechanisms are crucial for conscious awareness?
  • Do cortical feedback mechanisms transfer information from the peripheral visual cortex to central (foveal) visual cortex?
  • What is the relative contribution of the retinotectal and geniculostriate pathways to visual selection?
  • Are frontal and parietal regions that are crucial for spatial attention also critical for mental representations of numbers?
  • Is the top-down selection of spatial and feature-based visual information controlled by a single global mechanism or by a series of coordinated sub-systems?
  • What is the genotypic basis of selective attention in humans?

Current collaborations in attention/awareness:
Dr Sven Bestmann (University College London)
Dr Mark Bellgrove (University of Queensland)
Dr Elena Rusconi (University of Trento)
Dr Christian Ruff (University of Zurich)
Dr Petroc Sumner (Cardiff University)
Dr Mark Williams (Macquarie University)

2. Cognitive Control

Current team members: Rachel Adams, Chris Allen, Rory Cutler, Charles Hounsell, Leah Maizey, Sinead Morrison, Jemma Sedgmond, Solveiga Stonkute, Frederick Verbruggen

Neural mechanisms of cognitive control enable us to coordinate, execute, and update behaviour. The prefrontal cortex has long been associated with cognitive control but the architecture of the prefrontal system is one of the great unsolved mysteries in cognitive neuroscience. Within the broad field of cognitive control (or ‘executive functions’), our research focuses on understanding the neural basis of response inhibition, response selection, and the link between inhibition and risk-taking (including gambling and eating behaviour), principally through the application of TMS and tDCS. Specifically we aim to address the following questions:

  • How do prefrontal and parietal cortex support cognitive control in the human brain?
  • How do neural mechanisms of response inhibition interact with functionally related processes, such as response selection, attention, working memory, and risk-taking behaviour?
  • Can training people in basic motor inhibition enhance control? If so, what is neural mechanism underlying such effects?
  • How do neural mechanisms of cognitive control and emotional regulation interact?
  • What is the balance between domain specific and domain non-specific processing in the prefrontal cortex?

Current collaborations in cognitive control:
Dr Adam Aron (University of California, San Diego)
Dr Mark Bellgrove (University of Queensland)
Dr Xavier Caseras (Cardiff University)
Dr Natalia Lawrence (Cardiff University)
Dr Frederick Verbruggen (University of Exeter)

3. Concurrent TMS, MRI, and EEG

Current team members:  Chris Allen, Charles Hounsell, Leah Maizey, Jemma Sedgmond

The combination of TMS and neuroimaging (MRI, EEG) provides a unique window on human brain function, with broad applications and implications across the cognitive and clinicial neurosciences. By applying TMS within the MRI scanner, we can directly observe the physiological consequences of stimulation both locally (at the site of stimulation) and in remote interconnected brain regions. The integration of TMS and different imaging techniques also holds great promise for revealing the mechanism by which TMS influences neurophysiology and neurovascular coupling.

We have recently established concurrent TMS-MRI at CUBRIC via the Academic Expertise for Business (A4B) grant programme, an initiative of the Welsh Assembly Government that funds links between academia and industry in Wales. Our industrial partners on this project are Welsh neuromedical companies Magstim and Dymed.

Current collaborations in TMS-MRI:
Dr Sven Bestmann (University College London)
Dr John Evans (Cardiff University)
Prof. Derek Jones (Cardiff University)
Prof. Krish Singh (Cardiff University)
Prof. Richard Wise (Cardiff University)
Industry: Robin Davies (Magstim) and Mike Polson (Dymed)

4. TMS Methods

The application of TMS in cognitive neuroscience carries a variety of technical and interpretative challenges. As a ‘neurodisruption’ method, one critical issue is the control of TMS intensity. What strength of TMS is sufficient to yield effective (but not excessive) stimulation of cortical tissue? We have found that the extent of cortical activity during TMS is steeply related to the distance between the scalp and cortex. Even a difference of 1mm in the scalp-cortex distance between different sites can have a measurable and reliable effect on TMS-evoked behaviour. We have therefore developed a linear scaling method for calibrating the intensity of TMS according to scalp-cortex distance, thus enabling more precise and comparable stimulation of different regions. We are also developing a new type of brain atlas for TMS that maps regional variation in scalp-cortex distance over a large sample of subjects.

Current collaborations in TMS methods:
Dr Mark Stokes (University of Oxford)

5. The relationship between science and the media - the Insciout project

We are interested in how press releases issued by universities and academic journals influence the reporting of science news in the media. By understanding these positive and negative effects we aim to formulate an evidence-based policy for maximizing the impact and accuracy of science-related public relations. This project is supported by an ESRC transformative grant, the Wellcome Trust, and the British Psychological Society. For more information see www.insciout.com

Current collaborations in science and the media:
Prof Jacky Boivin
Dr Lewis Bott
Prof Jenny Kitzinger
Prof Petroc Sumner
Dr Andy Williams

6. The Evidence Information Service

We are developing a new service to facilitate communication between academic researchers and UK politicians and civil servants. The aim of the Evidence Information Service (EIS) will be to act as a rapid matchmaking and advisory service, connecting politicians with experts in academia and industry. The EIS will host a database of scientists who are willing to commit their time voluntarily to help policy makers obtain and interpret the most reliable evidence on specific issues. Such activities will include the provision and explanation of peer-reviewed literature, statistical consulting, and the critical assessment of data or conclusions.

For more information on the EIS see our public launch material and associated research project:
http://www.theguardian.com/science/2014/mar/18/research-scientific-evidence-information-service-politicians-eis
http://www.theguardian.com/science/blog/2014/mar/18/evidence-information-service-uk-politicians
http://blogs.lse.ac.uk/impactofsocialsciences/2014/05/12/evidence-information-service/

Current collaborations on the Evidence Information Service:
Dr Natalia Lawrence
Dr Sven Bestmann
Dr Andrew Kythreotis
Dr Gerard O’Grady

Funding

Current Major Grants

Chambers, C.D., Verbruggen, F.L.J., Boy, F., Dymond, S. & Lawrence, N. Wellcome Trust ISSF Seedcorn grant (U.K.), ‘Can GABAergic brain stimulation promote risk aversion in gambling?’, 2013-2014 (£33,572)

Chambers, C.D. & Verbruggen, F.L.J. BBSRC Project Grant (U.K.), ‘Neural dynamics of response inhibition and gambling across the lifespan’, 2013-2016 (£882,321)

Verbruggen F.L.J, Chambers, C.D., Lavric, A. & McLaren, I. Economic and Social Research Council (U.K.) ‘Do executive motor-control mechanisms regulate monetary choice and gambling?’, 2012-2015 (£546,626)

Bellgrove, M.A., Hester, R., Chambers, C.D., Garavan, H. & Hawi, Z. National Health and Medical Research Council project grant (Australia) ‘Genetic and physiological mechanisms of executive control’, 2011-2014 ($541,048)

Previous Major Grants

Chambers, C.D., Singh, K., Wise, R., Jones, D., Jiles, D, & Bestmann, S. Academic Expertise For Business grant (Welsh Assembly) ‘The integrated brain imaging and stimulation project (IBIS)’, 2010-2013 (£349,885)

Chambers, C.D. BBSRC David Phillips Fellowship (U.K.), ‘Investigating the neural basis of selective attention in the human brain: A combined neurodisruption and neuroimaging study, 2006-2011 (£421,754)

Chambers, C.D. & Driver, J. BBSRC Project Grant (U.K.), ‘Multisensory dynamics of selective attention in the human brain: A combined neurodisruption and neuroimaging project’, 2007-2011 (£403,884)

Bellgrove, M.A. & Chambers, C.D. ARC Project Grant (Australia), 'The cognitive neuroscience of executive control: behavioural, physiological and genetic mechanisms’, 2007-2010 ($319,000)

Previous Minor Grants

Varnava, A., & Chambers, C.D. Wales Institute of Cognitive Neuroscience Project Grant (U.K.). ‘The predictive nature of pseudoneglect for simulated visual neglect following unilateral parietal disruption using theta burst stimulation (TBS)’, 2009-2011 (£16,216)

Zhang, W., Klemen, J. & Chambers, C.D. Wales Institute of Cognitive Neuroscience Project Grant (U.K.). ‘The effect of crossmodal attentional load on sensory processing and the control of attentional resources’, 2009-2011 (£4,500)

Kurniawan, V., Klemen, J. & Chambers, C.D. Wales Institute of Cognitive Neuroscience Project Grant (U.K.). ‘Multisensory spatial and feature-based attention’, 2009-2011 (£4,500)

Allen, C. & Chambers, C.D. Wales Institute of Cognitive Neuroscience Project Grant (U.K.). ‘Probing the neural basis of visual awareness using transcranial magnetic stimulation (TMS)’, 2009-2011 (£5,625)

Klemen, J., Jones, D., Menz, M. & Chambers, C.D. Wales Institute of Cognitive Neuroscience Project Grant (U.K.). ‘Establishing anatomical connectivity of multisensory perception and attentional control using diffusion tensor imaging’, 2009-2011 (£3,750)

Klemen, J. & Chambers, C.D. Wales Institute of Cognitive Neuroscience Project Grant (U.K.), ‘Top-down control of crossmodal attention and its effects on sensory processing’, 2008-2011 (£15,000)

Research group

The TMS group is made up of staff and students from a wide range of backgrounds, including physics, neuroscience, and experimental psychology.

Lab head: 
Dr Chris Chambers

Postdoctoral Research Fellows:
Dr Chris Allen

Honourary Research Fellows:
Prof Frederick Verbruggen

Lab Manager:
Jemma Sedgmond

Research Assistants:
Sinead Morrison

Graduate Students:
Rachel Adams, PhD
Emma Cheetham, PhD
Rory Cutler, PhD
Charles Hounsell, PhD
Leah Maizey, PhD
Solveiga Stonkute, PhD

Current Undergraduate Students:
TBA

Interns:
Heidi Castle

Alumni:
Dr Andreas Bungert
Dr Jane Klemen
Veldri Kurniawan
Marcel Meyer
Dr Alice Varnava

Postgraduate research interests

I am happy to discuss projects that fall within the scope of:

Psychological and neural mechanisms of selective attention and conscious awareness

Human cognitive control processes, including response inhibition, response selection, working memory, and decision making under risk

Concurrent TMS and brain imaging

Methodological advances in TMS

Current students

Rachel Adams, PhD
Emma Cheetham, PhD
Rory Cutler, PhD
Charles Hounsell, PhD
Leah Maizey, PhD

Previous students

Chris Allen
Veldri Kurniawan
Marcel Meyer
Bertram Schenkluhn, Diplomarbeit, 2006-2007, University College London
Adam Morris, PhD, 2003-2008, University of Melbourne
Jonathan Payne, DPsych, 2002-2005, University of Melbourne

Undergraduate education

Bachelor of Science (Behavioural) with Honours (1st class), Monash University, 1998

Postgraduate education

PhD in Experimental Psychology, Monash University, 2002
Chartered Psychologist (CPsychol), British Psychological Society, 2011

Awards/external committees

Chair of the Registered Reports Committee, Center for Open Science 2014
Advisory Committee, Science Media Centre 2014
Fellow of the British Psychological Society (FBPsS), 2011
Spearman Medal, British Psychological Society, 2007
BBSRC David Phillips Fellowship, 2006-2011
Australian Academy of Science, European Travelling Fellowship, 2004

Employment

Professor of Cognitive Neuroscience
Head of Brain Stimulation, CUBRIC

Previous Appointments

Senior Research Fellow, Head of the CUBRIC Transcranial Magnetic Stimulation (TMS) Group, Cardiff University (2008-2014)
BBSRC David Phillips Fellow, School of Psychology, Cardiff University (2008-2011)
BBSRC David Phillips Fellow, Institute of Cognitive Neuroscience, University College London (2006-2008)
NHMRC Senior Postdoctoral Research Fellow, University of Melbourne, Australia (2004-2006)
NHMRC Postdoctoral Research Fellow, University of Melbourne, Australia (2002-2004)

Memberships

Chartered Member, British Psychological Society
Society for Neuroscience
Association of British Science Writers (ABSW)

Journal Editorships

Section Editor, AIMS Neuroscience
Section Editor, Cortex
Academic Editor, PLOS ONE

Manuscript reviewing activities

Addiction
Annals of the New York Academy of Sciences
Behavior Research Methods, Instruments and Computers
Biological Psychiatry
Brain and Cognition
Brain Research
Brain Stimulation
Brain Structure and Function
Cerebral Cortex
Cognition
Cognitive Brain Research
Cortex
Current Biology
Drug and Alcohol Dependence
eLife
European Journal of Neurology
Experimental Brain Research
Experimental Psychology
Human Brain Mapping
Journal of Cognitive Neuroscience
Journal of Experimental Psychology: General
Journal of Experimental Psychology: Human Perception and Performance
Journal of Neurophysiology
Journal of Neuroscience
Journal of the International Neuropsychological Society
Journal of Psychopharmacology
Nature
Neuroimage
Neuropsychologia
Neuropsychology
Neuroscience
Neuroscience Letters
Open Biology
Perception & Psychophysics
PLOS Biology
PLOS ONE
Psychiatry Research
Psychological Research
Psychological Science
Psychonomic Bulletin & Review
Trends in Cognitive Sciences

Grant reviewing activities

Biotechnology and Biological Sciences Research Council (BBSRC)
Economic and Social Research Council (ESRC)
Leverhulme Trust
Medical Research Council (MRC)
National Science Foundation
Netherlands Organisation for Scientific Research (NOW)
Neurological Foundation of New Zealand
Wellcome Trust

Invited Talks (2006 onwards)

Royal Society, London, 2014
Association for Psychological Science, San Francisco, USA, 2014
Department of Psychology, University of California San Diego, 2014
Amsterdam Medical Centre, Netherlands, 2014
Science Media Centre, London, 2014
School of Psychology and Psychiatry, Monash University, Australia, 2013
Australasian Cognitive Neuroscience Conference, Monash University, Australia, 2013
School of Psychology, University of Birmingham, 2013
University of California San Diego, USA, 2013
School of Psychology & Clinical Language Sciences, University of Reading, 2013
Department of Psychology, University of Amsterdam, Netherlands, 2013
School of Experimental Psychology, University of Bristol 2013
Japan Neuroscience Society Meeting, Kyoto 2013
School of Psychology, University of Sussex 2013
Department of Experimental Psychology, University of Oxford 2013
Division of Psychology, University of Abertay Dundee 2013
National Assembly for Wales, Cross-party Group on Science and Technology, Cardiff 2013
Royal Institution, London 2012
School of Psychology, University of Exeter 2012
CASE Europe Conference, Birmingham 2012
Department of Psychiatry, CHU Brugmann, Brussels, Belgium, 2011
Macquarie Centre for Cognitive Science, Macquarie University, Australia, 2011
MARCS Auditory Labs, University of Western Sydney, Australia, 2011
Department of Psychology, Royal Holloway, 2010
Centre for Mind/Brain Sciences, University of Trento, Italy, 2009
Welsh Branch of the British Psychological Society, Cardiff, 2009
Queensland Brain Institute, University of Queensland, Australia, 2009
Macquarie Centre for Cognitive Science, Macquarie University, Australia, 2009
Queensland Brain Institute, University of Queensland, Australia, 2009
Themed speaker, Young Neuroscientist Day, Cardiff University, 2008
Spearman Medal Lecture, BPS Annual Conference, Dublin, 2008
Department of Psychology, Trinity College Dublin, 2008
FMRIB Centre, University of Oxford, 2007
Psychology Department, University of California San Diego, 2007
School of Psychology, Cardiff University, 2007
School of Psychology, University of Queensland, Australia, 2007
Moss Rehabilitation Research Institute, Philadelphia, 2006
Chaucer Club Presentation, MRC CBU, University of Cambridge, 2006
Cognitive Neuroscience Research Unit, University of Durham, 2006
Institute of Cognitive Neuroscience, University College London, 2006
School of Psychology, University of Birmingham, 2006
Department of Psychology, University College London, 2006